Evidence map›Paper›PMID 40697529›Full record

ArticleLancet regional health. Americas2025

Carbapenemases producing gram-negative bacteria surveillance in Latin America and the caribbean: a retrospective observational study from 2015 to 2020.

Marcelo Pillonetto, Priscila Lamb Wink, Roberto G Melano, María Antonieta Jiménez-Pearson, Nancy Lorena Melgarejo Touchet, Sandra Yamile Saavedra Rojas, Debora N O Kulek, Andre Luiz Abreu, Renata Tigulini Peral, Rogerio Miorando and 7 more

Abstract read
In one paragraph

Article in Lancet regional health. Americas, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed.

  1. Article
  2. Review
  3. Microbiology spectrum · 2026
    Article
  4. In vitro activity of aztreonam-avibactam against carbapenem-resistant Pseudomonas aeruginosa from Southern Brazil.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2026
    Article
  5. Article
  6. Article
  7. ConsistentAntimicrobial agents and chemotherapy · 2026
    Article
  8. Review
  9. Review
  10. Article
  11. Emergence of KPC-producingAntimicrobial agents and chemotherapy · 2026
    Article
  12. Article
  13. Expanding Threat of Carbapenemase-ProducingbioRxiv : the preprint server for biology · 2026
    Article
  14. Article
  15. Co-occurrence of blaBMC microbiology · 2026
    Article
  16. Epidemiological Insights into Carbapenem-ResistantAntibiotics (Basel, Switzerland) · 2026
    Article
  17. Article
  18. Observational
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Marcelo PillonettoLaboratorio Central de Saúde Pública do Paraná, São José dos Pinhais, PR, Brazil.
Priscila Lamb WinkPan American Health Organization, Antimicrobial Resistance Team, AMR Special Program, Washington, DC, USA.
Roberto G MelanoPan American Health Organization, Antimicrobial Resistance Team, AMR Special Program, Washington, DC, USA.
María Antonieta Jiménez-PearsonCentro Nacional de Referencia de Bacteriología, Instituto Costarricense de Investigación y Enseñanza en Nutrición y Salud (Inciensa), Cartago, Costa Rica.
Nancy Lorena Melgarejo TouchetSección Antimicrobianos, Dpto. Bacteriología y Micología, Laboratorio Central de Salud Pública, Ministerio de Salud Pública y Bienestar Social, Paraguay.
Sandra Yamile Saavedra RojasGrupo Microbiología, Dirección Redes en Salud Pública, Subdirección Laboratorio Nacional de Referencia, Instituto Nacional de Salud Colombia, Bogotá, Colombia.
Debora N O KulekCoordenação Geral de Laboratórios de Saúde Pública, Secretaria de Vigilância em Saúde e Ambiente, Ministério da Saúde, Brasília, DF, Brazil.
Andre Luiz AbreuCoordenação Geral de Laboratórios de Saúde Pública, Secretaria de Vigilância em Saúde e Ambiente, Ministério da Saúde, Brasília, DF, Brazil.
Renata Tigulini PeralCoordenação Geral de Laboratórios de Saúde Pública, Secretaria de Vigilância em Saúde e Ambiente, Ministério da Saúde, Brasília, DF, Brazil.
Rogerio MiorandoDepartamento de Engenharia de Produçao, Universidade Federal de Santa Catarina, Florianópolis, SC, Brazil.
Hatim SatiWorld Health Organization, AMR Division, Geneva, Switzerland.
Genara Romero ThomasPan American Health Organization, Antimicrobial Resistance Team, AMR Special Program, Washington, DC, USA.
Marcelo GalasPan American Health Organization, Antimicrobial Resistance Team, AMR Special Program, Washington, DC, USA.
Pilar Ramon PardoPan American Health Organization, Antimicrobial Resistance Team, AMR Special Program, Washington, DC, USA.
Carlos R V KifferGrupo de Análises em Infecções e Antimicrobianos (GAIA), Laboratório Especial de Microbiologia Clínica (LEMC), Disciplina de Infectologia, Escola Paulista de Medicina (EPM), Universidade Federal de São Paulo (UNIFESP), São Paulo, SP, Brazil.
Ana Paula D'Alincourt Carvalho AssefLaboratório de Bacteriologia Aplicada a Saúde Única e Resistência Antimicrobiana (LabSUR), Instituto Oswaldo Cruz/FIOCRUZ, Rio de Janeiro, RJ, Brazil.
CARBA-LAC Group

Funding

World Health Organization 001
6 · The paper itself

Abstract

Background: The rise of multidrug-resistant (MDR) bacteria represents a public health threat, with carbapenem resistance exacerbating this challenge. This study investigates carbapenemase-producing bacteria (CPB) across the Latin America and the Caribbean (LAC) region. Methods: A retrospective observational study was conducted across 12 LAC countries from 2015 to 2020. A total of 58,909 isolates were analyzed utilizing polymerase chain reaction (PCR) to detect key carbapenemases in Enterobacterales, Findings: 47,804/58,909 (81.14%) carbapenemases were identified, with Brazil accounting for 73% of these. The majority were reported in carbapenem-resistant Enterobacterales-CRE (65.33%; 31,230/47,804), followed by carbapenem-resistant ABC-CRAB (22.05%; 10,542/47,804), and carbapenem-resistant Interpretation: This study highlights a high prevalence of CPB in LAC, with a stable trend in Funding: None.

Indexed as

Antimicrobial resistanceCarbapenemasesLatin AmericaMultidrug-resistant bacteriaPublic health challenge

Identifiers

PMID40697529
PMCPMC12281157

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.