Evidence map›Paper›PMID 40697406›Full record

ArticleBMJ public health2025

ParkProReakt-evaluation of a proactive approach to healthcare in Parkinson's disease: a study protocol for a randomised controlled trial.

Marlena van Munster, Johanne Stümpel, Anna J Pedrosa, Kati Niemand, Ingmar Wellach, Dirk Becker, Isabel Doblinger, Kristina Schmidt, René Reiners, Daniel Wolferts and 25 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMJ public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

35 authors.

Marlena van MunsterDepartment of Neurology, Philipps-Universität Marburg, Marburg, Germany.
Johanne StümpelDepartment of Neurology, Philipps-Universität Marburg, Marburg, Germany.ORCID https://orcid.org/0000-0002-3690-1295
Anna J PedrosaDepartment of Neurology, Philipps-Universität Marburg, Marburg, Germany.
Kati NiemandDepartment of Neurology, Philipps-Universität Marburg, Marburg, Germany.
Ingmar WellachPraxis für Neurologie und Psychiatrie Hamburg Walddörfer, Hamburg, Germany.
Dirk BeckerPraxis für Neurologie und Psychiatrie Hamburg Walddörfer, Hamburg, Germany.
Isabel DoblingerPraxis für Neurologie und Psychiatrie Hamburg Walddörfer, Hamburg, Germany.
Kristina SchmidtPraxis für Neurologie und Psychiatrie Hamburg Walddörfer, Hamburg, Germany.
René ReinersFraunhofer Institute for Applied Information Technology FIT, Sankt Augustin, Germany.
Daniel WolfertsFraunhofer Institute for Applied Information Technology FIT, Sankt Augustin, Germany.
Anika MartinFraunhofer Institute for Applied Information Technology FIT, Sankt Augustin, Germany.
Marius NisslmüllerFraunhofer Institute for Applied Information Technology FIT, Sankt Augustin, Germany.
Keywan SohrabiFaculty of Medicine, Institute of Medical Informatics, Justus Liebig University Giessen, Giessen, Germany.
Volker GroßFaculty of Health Sciences, University of Applied Sciences, Giessen, Germany.
Birgit SamansFaculty of Health Sciences, University of Applied Sciences, Giessen, Germany.
Patrick FischerFaculty of Health Sciences, University of Applied Sciences, Giessen, Germany.
Mohammed Osman AshrafFaculty of Health Sciences, University of Applied Sciences, Giessen, Germany.
Rebecca WichartzFaculty of Health Sciences, University of Applied Sciences, Giessen, Germany.
Marcin GrzegorzekInstitute for Medical Informatics, University of Lübeck, Lübeck, Germany.
Xinyu HuangInstitute for Medical Informatics, University of Lübeck, Lübeck, Germany.
Artur PietInstitute for Medical Informatics, University of Lübeck, Lübeck, Germany.
Mona IrsfeldInstitute for Medical Informatics, University of Lübeck, Lübeck, Germany.
Christian TrenseInstitute for Medical Informatics, University of Lübeck, Lübeck, Germany.
Paulina M OlgemöllerFaculty of Medicine and University Hospital Cologne, Medical Psychology / Neuropsychology and Gender Studies, University of Cologne, Köln, Germany.
Ümran SevenFaculty of Medicine and University Hospital Cologne, Medical Psychology / Neuropsychology and Gender Studies, University of Cologne, Köln, Germany.
Ann-Kristin FolkertsFaculty of Medicine and University Hospital Cologne, Medical Psychology / Neuropsychology and Gender Studies, University of Cologne, Köln, Germany.
Elke KalbeFaculty of Medicine and University Hospital Cologne, Medical Psychology / Neuropsychology and Gender Studies, University of Cologne, Köln, Germany.
Hannes BöbingerInnovationsfonds & Produktportfolio, Techniker Krankenkasse, Hamburg, Germany.
Jens DapperAWO Stadtkreis Giessen e.V, Giessen, Germany.
Lars WohlfahrtAWO Stadtkreis Hamburg e.V, Hamburg, Germany.
Max GeraedtsInstitute for Health Services Research and Clinical Epidemiology, Philipps-Universität Marburg, Marburg, Germany.
Natalie AltschuckInstitute for Health Services Research and Clinical Epidemiology, Philipps-Universität Marburg, Marburg, Germany.
Linda KerkemeyerLiKe Healthcare Research GmbH, Berlin, Germany.
Carsten EggersDepartment of Neurology, Philipps-Universität Marburg, Marburg, Germany.
David J PedrosaDepartment of Neurology, Philipps-Universität Marburg, Marburg, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: The complexity of Parkinson's disease (PD) symptoms and the necessity for individualised, multidisciplinary and digital health technology-based care are widely acknowledged; however, access to specialist care remains limited, particularly in rural areas. Current healthcare systems are frequently ill-equipped to deliver timely, personalised interventions. In response to these challenges, the ParkProReakt project aims to enhance PD care through a proactive, technology-enabled, multidisciplinary approach designed to improve patient health-related quality of life (HRQoL) and alleviate caregiver burden. Methods and analysis: A randomised controlled trial will assess the efficacy and cost-effectiveness of ParkProReakt-a proactive, multidisciplinary, digitally supported care model for community-dwelling people with Parkinson's disease (PwPD)-compared with standard care. We will recruit a total of 292 PwPD and their informal caregivers living in two diverse regions in Germany. The primary outcome measure will be patients' HRQoL as measured by the Parkinson's Disease Questionnaire, obtained at baseline, monthly and at completion of participation. Secondary outcomes comprise patients' subjective well-being, incidence or change of long-term care needs, global cognition and disease progression, utilisation of healthcare services, including hospitalisations, caregiver burden and healthcare costs. Statistical analysis will include t-tests for HRQoL changes, general linear model for confounders and multilevel models for centre effects. Secondary outcomes and cost-effectiveness (incremental cost-effectiveness ratio) will be analysed similarly using R and SPSS. Ethics and dissemination: The study protocol has been approved by the Ethics Committees of the Medical Associations of Hesse and Hamburg. The results of our study will be reported to the funding body and disseminated through scientific publications and presentations at national and international conferences. Trial registration number: This study was registered with the German Registry for Clinical Studies (DRKS) in both German and English; number: DRKS00031092.

Indexed as

Data CollectioneconomicsPublic Health

Identifiers

PMID40697406
PMCPMC12281329

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.