Evidence map›Paper›PMID 40697360›Full record

ArticleJID innovations : skin science from molecules to population health2025

Myeloid and Mast Cell Progenitors Are Elevated in Atopic Dermatitis.

Katie Ridge, Barry Moran, Mark A Little, Cliona O'Farrelly, Jean Dunne, Julianne Clowry, Clodagh Loftus, Conor M Finlay, Alan D Irvine, Niall Conlon

Abstract read
In one paragraph

Article in JID innovations : skin science from molecules to population health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Katie RidgeUCARE Centre, Clinical and Diagnostic Immunology, St. James's Hospital, Dublin, Ireland.
Barry MoranTrinity Biomedical Sciences Institute, School of Biochemistry and Immunology, Trinity College Dublin, Dublin, Ireland.
Mark A LittleClinical Medicine, School of Medicine, Trinity College Dublin, Dublin, Ireland.
Cliona O'FarrellyClinical Medicine, School of Medicine, Trinity College Dublin, Dublin, Ireland.
Jean DunneUCARE Centre, Clinical and Diagnostic Immunology, St. James's Hospital, Dublin, Ireland.
Julianne ClowryClinical Medicine, School of Medicine, Trinity College Dublin, Dublin, Ireland.
Clodagh LoftusDermatology, St. James's Hospital, Dublin, Ireland.
Conor M FinlayClinical Medicine, School of Medicine, Trinity College Dublin, Dublin, Ireland.
Alan D IrvineClinical Medicine, School of Medicine, Trinity College Dublin, Dublin, Ireland.
Niall ConlonUCARE Centre, Clinical and Diagnostic Immunology, St. James's Hospital, Dublin, Ireland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chronic spontaneous urticaria and atopic dermatitis (AD) are chronic skin disorders characterized by itch. Although mast cells play an integral role in the pathogenesis of chronic spontaneous urticaria, their role in AD is unclear, having a contributory role in a disease largely driven by T helper 2 polarization. Despite this, the role of mast cells in AD is important, given their release of proinflammatory mediators. Recently, myeloid and mast cell progenitors were identified as potential biomarkers for treatment response in chronic spontaneous urticaria. These Lin

Indexed as

Atopic dermatitisImmunologyMast cellsMyeloid cellsTranslational medicine

Identifiers

PMID40697360
PMCPMC12280991

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.