Efficacy of manipulation under anesthesia with ultrasound-guided platelet-rich plasma injection in shoulder stiffness concomitant with rotator cuff injury.

Hypothesis and Background: Manipulation under anesthesia (MUA), combined with ultrasound-guided platelet-rich plasma injection, is expected to yield favorable functional outcomes in cases of shoulder stiffness concomitant with rotator cuff injury (RCI). Little has been reported on the efficacy of MUA with ultrasound-guided platelet-rich plasma injection for shoulder stiffness concomitant with RCI. Methods: Beginning from August 2023, 30 patients with shoulder stiffness accompanied by RCI were enrolled in the study. All participants underwent MUA, accompanied by ultrasound-guided platelet-rich plasma injection at our institution. We collected and evaluated demographic data for each subject, as well as their range of motion (ROM), visual analog scale pain scores, Constant-Murley Scores, Western Ontario Rotator Cuff Index, and magnetic resonance imaging images. These assessments were conducted before the operation and at 2 weeks, 6 weeks, 3 months, 6 months, and 12 months postoperation. Results: All patients exhibited a significantly improved ROM following the operation: forward flexion increased from 58.70° ± 6.01° to 154° ± 3.59° ( Conclusion: Patients with shoulder stiffness and concomitant RCI can achieve satisfactory functional outcomes following MUA combined with ultrasound-guided platelet-rich plasma injection therapy. Further studies are necessary for a more detailed analysis of subgroups and for long-term follow-up.