ReviewNanomedicine (London, England)2025
Carbon-based nanotechnology for Parkinson's disease: diagnostic and therapeutic innovations.
Review in Nanomedicine (London, England), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed, 1 synthesis or guideline pooled it.
- MicroRNA-7: a versatile player and core target in brain disorders.Journal of translational medicine · 2026Pooled it
- Pathogenesis-Driven Drug Repurposing with a Self-Nanoemulsifying Delivery System for Parkinson's Disease.Pharmaceuticals (Basel, Switzerland) · 2026Review
- From Bench to Brain: Translating EV and Nanocarrier Research into Parkinson's Disease Therapies.Biology · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Neurodegenerative diseases encompass a number of disorders that share a core pathological feature of progressive neuronal damage and loss. Parkinson's disease (PD) is a progressive neurodegenerative disorder marked by the degeneration of dopaminergic neurons and the accumulation of α-synuclein aggregates, leading to significant motor deficits. The current limitations in early diagnosis and targeted treatment present a critical need for innovative approaches. Carbon-based nanomaterials (CBNPs), such as graphene, carbon nanotubes (CNTs), and fullerenes, have emerged as promising tools in addressing these challenges due to their exceptional electrical, mechanical, and biocompatible properties. This review highlights the applications of CBNPs in PD, including their use as neuroprotective agents that mitigate oxidative stress, drug delivery systems capable of crossing the blood-brain barrier, and highly sensitive biosensors for early detection of PD biomarkers. Furthermore, recent advancements demonstrate their possible role as theranostic agents in PD. While the potential of CBNPs is significant, concerns regarding long-term safety, biocompatibility, and translational scalability remain. Continued research and refinement are essential to unlock the full clinical potential of CBNPs in the diagnosis and treatment of PD.
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Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.