Evidence map›Paper›PMID 40697099›Full record

SynthesisAnnals of medicine2025

Efficacy of probiotics pretreatment in

Yinghui Zhang, Mengtian Tu, Ping Long, Jing Zheng, Guanghong Du, Shiyu Xiao, Caiping Gao

Abstract readSystematic ReviewMeta-Analysis
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Annals of medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Antibiotics (Basel, Switzerland) · 2026
    Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yinghui ZhangDepartment of Gastroenterology, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, Chengdu, China.ORCID 0009-0003-3853-4497
Mengtian TuSichuan Provincial Center for Mental Health, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, Chengdu, China.
Ping LongDepartment of Gastroenterology, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, Chengdu, China.
Jing ZhengDepartment of Gastroenterology, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, Chengdu, China.
Guanghong DuGeriatric Department, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, Chengdu, China.
Shiyu XiaoDepartment of Gastroenterology, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, Chengdu, China.ORCID 0000-0002-4611-1457
Caiping GaoDepartment of Gastroenterology, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, Chengdu, China.ORCID 0000-0002-2299-0303

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundProbiotics inhibit

methodsWe searched PubMed, EMBASE, the Cochrane Library, and the Conference Proceedings Citation Index up to January 31, 2024, to identify randomized controlled studies (RCTs) assessing the efficacy of probiotics used before

resultsTwelve eligible RCTs with 2,144 participants were included. The intention-to-treat analysis revealed that the overall eradication rate of

conclusionThere is moderate to high evidence to suggest that probiotics pretreatment improves

Indexed as

Helicobacter InfectionsHelicobacter pyloriProbioticsAnti-Bacterial AgentsGastrointestinal MicrobiomeHumansRandomized Controlled Trials as TopicTreatment OutcomeAnti-Bacterial AgentsHelicobacter pylorimeta-analysismicrobiomepretreatmentprobiotics

Identifiers

PMID40697099
PMCPMC12288164

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.