Evidence map›Paper›PMID 40696937›Full record

ArticlePsychology & health2026

'I told them they had to get tested, and they did': social influence among siblings with Li-Fraumeni syndrome.

Chloe O Huelsnitz, Allison Werner-Lin, Ashley S Thompson, Camella J Rising, Rowan Forbes Shepherd, Jennifer L Young, Mark H Greene, Payal P Khincha

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PubMed Full text at PMC Publisher
In one paragraph

Article in Psychology & health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Chloe O HuelsnitzDivision of Cancer Control and Population Sciences, Behavioral Research Program, National Cancer Institute, Rockville, MD, USA.
Allison Werner-LinSchool of Social Policy and Practice, University of Pennsylvania, Philadelphia, PA, USA.
Ashley S ThompsonClinical Genetics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA.
Camella J RisingClinical Genetics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA.
Rowan Forbes ShepherdClinical Genetics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA.
Jennifer L YoungDepartment of Medical Social Science, Department of Psychiatry and Behavioral Sciences, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.
Mark H GreeneClinical Genetics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA.
Payal P KhinchaClinical Genetics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA.

Funding

Intramural NIH HHS Z99 CA999999
6 · The paper itself

Abstract

objectivesHealth-related social influence refers to individual efforts to change another person's health beliefs and/or behavior. We sought to understand perspectives on social influence among adult siblings in families with an inherited cancer syndrome, Li-Fraumeni Syndrome (LFS).

designAn interprofessional team conducted 16 semi-structured interviews with sibling groups (

main outcome measuresA semi-structured interview guide included questions targeting family closeness, information sharing, and perspectives on screening and cancer care. The research team collaboratively conducted thematic analysis on verbatim transcripts.

resultsParticipants reported attempts to influence their siblings' thoughts or behavior regarding LFS-related genetic testing and cancer screening, prevention, and treatment. Some participants expressed respect for sibling autonomy regarding risk management decisions. Others reported explicit attempts to change their siblings' perspective or behavior due to concern for their siblings' health.

conclusionFindings suggest participants believed their influence meaningfully affected siblings' LFS risk management, indicating such influence comprises a social intervention pathway with potential to increase cascade testing and to support risk management. However, for some siblings, such efforts incurred risk of relational conflict. Future research might aim to help adult siblings balance social influence strategies with relational maintenance behaviors.

Indexed as

Genetic TestingLi-Fraumeni SyndromeSiblingsAdolescentAdultAgedFemaleHumansInterviews as TopicMaleMiddle AgedYoung Adultfamiliesgenetic diseaseLi-Fraumeni syndromesiblingssocial influence

Identifiers

PMID40696937
PMCPMC13404146

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.