ArticleClinical & experimental ophthalmology2025
Association Between Prior Selective Laser Trabeculoplasty and Phaco-iStent Inject Efficacy.
Article in Clinical & experimental ophthalmology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Win Ratios in Ophthalmology-a Hierarchical Metric to Evaluate Adverse Outcomes in Comparative Studies.Ophthalmology science · 2026Article
- Association Between Prior Selective Laser Trabeculoplasty and Phaco-iStent Inject Efficacy.Clinical & experimental ophthalmology · 2025Article
- From first generation to the next: evolution and research trends in iStent technology.Frontiers in medicine · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTo evaluate the association between prior selective laser trabeculoplasty (SLT) on intraocular pressure (IOP) lowering efficacy of phacoemulsification combined with iStent inject (phaco-iStent).
methodsRetrospective study of 1550 eyes of 1023 patients with and without prior SLT that underwent phaco-iStent. Surgical success was defined at 12 months using three different endpoints: (A) IOP ≤ 21 mmHg and ≥ 20% IOP decrease, or ≥ 1 medication reduction vs. baseline, (B) ≥ 1 medication reduction with no increase in baseline IOP or (C) IOP ≤ 21 mmHg and ≥ 20% IOP decrease alone with no increase in baseline medication use. The prior SLT and no SLT patients were propensity score matched by age, baseline IOP and IOP-lowering medication use and visual field mean deviation (VF MD).
resultsThree hundred and sixty-eight eyes (184 eyes per group) of 313 patients were matched based on baseline IOP and medications, VF MD, and age at surgery. Prior SLT was associated with an increased risk of failure using endpoints A [hazards ratio (HR) 2.13, 95% confidence intervals (CI) 1.34-3.38], B (HR 1.73, CI 1.1-2.72) and C (HR 1.51, CI 1.05-2.16). In eyes with prior SLT, higher baseline IOP was significantly associated with a lower risk of failure to achieve a minimum 20% reduction in IOP from baseline (HR 0.89, 0.85-0.94, p < 0.001).
conclusionIn this observational study, prior SLT was associated with an increased risk of failure after phaco-iStent inject surgery. In eyes with prior SLT, there was a significantly decreased risk of failure in eyes with higher baseline IOP.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.