ArticleEnvironmental science & technology2025
Label-Free Identification and Imaging of Microplastic and Nanoplastic Biouptake Using Optical Photothermal Infrared Microspectroscopy.
Article in Environmental science & technology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed.
- Microplastics and Nanoplastics in Food: Dietary Toxicology Beyond Particle Counts.Comprehensive reviews in food science and food safety · 2026Review
- Autoencoder-Based Detection of Nanoplastics in Biological Matrices via Infrared Hyperspectral Imaging.ACS measurement science au · 2026Article
- Single-Particle Mid-Infrared Photothermal Imaging Reveals Hidden Heterogeneity in Real-World Micro- and Nanoplastics.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- The challenges ofEco-Environment & Health · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
As plastic waste breaks down into smaller fragments in the environment, it poses a significant threat to both terrestrial and aquatic ecosystems as well as exposed humans via contaminated water, air, and food. There is thus a critical need to understand the biological uptake and subsequent impacts of plastic particles in aquatic and terrestrial organisms. Yet, we lack effective and robust methodologies to identify and localize micrometer and nanometer-sized polymer particles in whole organisms. This proof-of-concept study introduces a label-free approach for the localization and identification of plastic particles within organisms utilizing optical photothermal infrared microscopy (O-PTIR) and microtome techniques. By integrating O-PTIR imaging with microtomy, we achieved high spatial resolution and sensitivity, allowing us to detect and identify different plastic particles (polystyrene, polyethylene, polypropylene, and poly(methyl methacrylate)) and confirm their localization in a tissue sample. The results demonstrate successful visualization of microplastics and nanoplastics at moderate exposure concentrations in a range of aquatic and terrestrial organisms; namely,
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.