Evidence map›Paper›PMID 40696775›Full record

ArticleJournal of the American Chemical Society2025

Autonomous Activation of a Gated Chemiluminescent Photosensitizer Enables Targeted Photodynamic Therapy in Tumor Cells.

Wenwu Peng, Tianjiao Zhou, Lifan Hu, Vivien Vankann, Toszka Bohn, Tobias Bopp, Seah Ling Kuan, Tanja Weil

Abstract read
In one paragraph

Article in Journal of the American Chemical Society, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Review
  2. Sequential HAngewandte Chemie (International ed. in English) · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Wenwu PengMax Planck Institute for Polymer Research, 55128 Mainz, Germany.
Tianjiao ZhouMax Planck Institute for Polymer Research, 55128 Mainz, Germany.
Lifan HuMax Planck Institute for Polymer Research, 55128 Mainz, Germany.
Vivien VankannInstitute of Immunology of the Research Center for Immunotherapy (FZI), University Medical Center, Johannes Gutenberg University Mainz, 55131 Mainz, Germany.
Toszka BohnInstitute of Immunology of the Research Center for Immunotherapy (FZI), University Medical Center, Johannes Gutenberg University Mainz, 55131 Mainz, Germany.
Tobias BoppInstitute of Immunology of the Research Center for Immunotherapy (FZI), University Medical Center, Johannes Gutenberg University Mainz, 55131 Mainz, Germany.
Seah Ling KuanMax Planck Institute for Polymer Research, 55128 Mainz, Germany.ORCID 0000-0003-3945-4491
Tanja WeilMax Planck Institute for Polymer Research, 55128 Mainz, Germany.ORCID 0000-0002-5906-7205

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chemiluminescence-based photodynamic therapy (CLPDT) offers a promising solution to the light penetration limits of traditional PDT. However, it lacks spatiotemporal control. Intracellularly activated, self-luminescent PDT agents

Indexed as

Antineoplastic AgentsPhotochemotherapyPhotosensitizing AgentsCell Line, TumorHumansLuminescenceReactive Oxygen SpeciesRutheniumSinglet OxygenAntineoplastic AgentsPhotosensitizing AgentsReactive Oxygen SpeciesRutheniumSinglet Oxygen

Identifiers

PMID40696775
PMCPMC12333359

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.