ArticleMedicine2025
Amlodipine overdose rescued with extracorporeal membrane oxygenation: A case report.
Article in Medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed.
- Article
- Massive Amlodipine Overdose Complicated by Multiorgan Failure and Cardiac Arrest: A Case Report.Clinical medicine insights. Case reports · 2025Article
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Authors and funding
5 authors.
Funding
Abstract
rationaleAmlodipine, a calcium channel blocker, is widely prescribed for managing hypertension through vascular smooth muscle relaxation. However, severe amlodipine toxicity can lead to profound hypotension and refractory shock, often unresponsive to conventional treatments. PATIENT CONCERNS: In this report, we reported a 32-year-old female case of amlodipine overdose who was admitted to our hospital on March 1, 2024, due to intentionally ingesting approximately 84 tablets of amlodipine (5 mg each). DIAGNOSES: Patient was diagnosed with amlodipine overdose and refractory shock.
interventionPatient was treated with extracorporeal membrane oxygenation (ECMO), invasive mechanical ventilation, and continuous renal replacement therapy. OUTCOMES: On March 7, the patient was successfully weaned off ECMO and discharged on March 15, 2024. During postoperative follow-up, the lung CT scan showed complete resolution of intrapulmonary exudates. LESSONS: The case prompts that early initiation of ECMO, following the failure of conventional medical interventions, was pivotal in stabilizing the patient's hemodynamics, offering a promising alternative in the management of severe calcium channel blocker toxicity.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.