Evidence map›Paper›PMID 40696640›Full record

ArticleMedicine2025

Emerging trends and disparities in mortality due to coexisting non-Hodgkin's lymphoma and respiratory infections: A U.S. nationwide retrospective analysis from 1999 to 2020.

Humza Saeed, Masab Ali, Muhammad Husnain Ahmad, Ilsa Babar, Sana Javeria, Zabeehullah, Ch Faizan Rasheed, Hiba Arshad Shahani, Aasim Sehbai

Abstract read
In one paragraph

Article in Medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Observational
  2. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Humza SaeedDepartment of Internal Medicine, Rawalpindi Medical University, Rawalpindi, Punjab, Pakistan.
Masab AliDepartment of Internal Medicine, Punjab Medical College, Faisalabad, Punjab, Pakistan.ORCID 0009-0007-8599-6861
Muhammad Husnain AhmadDepartment of Medicine, Tentishev Satkynbai Memorial Asian Medical Institute, Kant, Kyrgyzstan.ORCID 0009-0006-5248-0749
Ilsa BabarDepartment of Internal Medicine, King Edward Medical University, Lahore, Punjab, Pakistan.
Sana JaveriaDepartment of Medicine, Indian Institute of Medical Science And Research, Indewadi, Maharashtra, India.
ZabeehullahDepartment of Internal Medicine, Rawalpindi Medical University, Rawalpindi, Punjab, Pakistan.
Ch Faizan RasheedDepartment of Internal Medicine, Rawalpindi Medical University, Rawalpindi, Punjab, Pakistan.
Hiba Arshad ShahaniDepartment of Internal Medicine, Rawalpindi Medical University, Rawalpindi, Punjab, Pakistan.
Aasim SehbaiDepartment of Oncology, Alabama Cancer Care, Anniston, AL.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Non-Hodgkin lymphoma (NHL) patients are highly susceptible to respiratory infections due to immunosuppression from both the disease and its treatments. Understanding mortality trends and disparities in this population is crucial for improving care and reducing the burden of coexisting conditions. This study analyzed death certificates from the Center of Disease Control Wide-Ranging Online Data for Epidemiologic Research database for individuals aged ≥ 25 years who died between 1999 and 2020 with both NHL and respiratory infections. Age-adjusted mortality rates (AAMRs) and annual percent change were computed by year, gender, age group, race/ethnicity, geographic region, and urbanization status. From 1999 to 2020, 66,986 deaths were related to coexisting NHL and respiratory infections. AAMR decreased from 17.1 to 14.6 per 1,000,000 individuals. A significant decline in AAMR occurred between 1999 and 2018, followed by a significant rise from 2018 to 2020. Men had nearly double the AAMR compared to women. Older adults had the highest AAMRs, followed by middle-aged adults and young adults. Among racial and ethnic groups, non-Hispanic (NH) White individuals had the highest AAMR, followed by NH American Indian or Alaska Natives, Hispanic or Latino, NH Asian or Pacific Islanders, and NH Black or African American populations. Non-metropolitan areas had a higher AAMR than metropolitan areas. The overall AAMR decreased from 1999 to 2020, but a significant rise was observed in recent years. Mortality disparities were notable among men, older adults, NH White individuals, and residents of non-metropolitan areas, underscoring the need for targeted interventions to address these disparities.

Indexed as

Health Status DisparitiesLymphoma, Non-HodgkinRespiratory Tract InfectionsAdultAgedAged, 80 and overEthnicityFemaleHumansMaleMiddle AgedMortalityRetrospective StudiesUnited Statesdisparitiesgender trendsmortalitynon-Hodgkin lymphomaracial trendsrespiratory infections

Identifiers

PMID40696640
PMCPMC12282841

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.