Evidence map›Paper›PMID 40696579›Full record

ArticleMedicine2025

Eosinophilic gastroenteritis with negative endoscopic biopsy and no peripheral eosinophilia: A case report.

Yukai Chen, Keke Sun, Linbo Chen, Dewen Lu, Chihong Shi, Qi Lin

Abstract readCase Reports
In one paragraph

Article in Medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yukai ChenDepartment of Gastroenterology, The Affiliated People's Hospital of Ningbo University, Ningbo, Zhejiang Province, China.
Keke Sun
Linbo Chen
Dewen Lu
Chihong Shi

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

rationaleEosinophilic gastroenteritis (EoGE) is a rare inflammatory disease that can affect the entire gastrointestinal tract. Klein et al classified EoGE into 3 distinct subtypes according to the depth of eosinophilic infiltration: mucosal, muscular, and serosal. PATIENT CONCERNS: We herein report a case of a 29-year-old woman who presented with abdominal pain, nausea, and vomiting, with no history of adverse reactions to any allergens. Laboratory test results revealed a normal count of peripheral blood eosinophils. Ultrasound and computed tomography revealed thickened intestinal walls and ascites in both the abdominal cavity and the pelvic cavity. Multiple endoscopic biopsies targeting several swelling segments of the intestinal wall revealed no increase in the number of eosinophils. DIAGNOSES: The constellation of clinical, laboratory, radiological findings, histopathological data, and the excellent response to corticosteroids led to a diagnosis of EoGE for the patient.

interventionsThe patient was treated with corticosteroids. OUTCOMES: Symptoms improved rapidly, and the thickened intestinal walls returned to a typical level. LESSONS: EoGE should be considered scrupulously, even if the count of eosinophils is in the normal range and the endoscopic biopsy is negative. Obtaining pathology of ascites as much as possible and taking a multisite biopsy sample, including both targeted and random biopsies, may improve the diagnostic rate.

Indexed as

EnteritisEosinophiliaGastritisAbdominal PainAdultBiopsyEndoscopy, GastrointestinalFemaleHumansascitesbiopsydiagnosiseosinophilic gastroenteritis

Identifiers

PMID40696579
PMCPMC12282817

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.