Evidence map›Paper›PMID 40696447›Full record

ArticleJournal of medical case reports2025

Magnesium sulfate toxicity successfully managed with hemodialysis: a case report.

Mahdieh Miri, Farhad Esmailsorkh, Ehsan Farhadi, Mitra Rahimi

Abstract readCase Reports
In one paragraph

Article in Journal of medical case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Mahdieh MiriDepartment of Internal Medicine, Saveh University of Medical Science, Saveh, Markazi, Iran.
Farhad EsmailsorkhSchool of Medicine, Shahid Beheshti University of Medical Science, Tehran, Iran. farhad.esmailsorkh@gmail.com.ORCID http://orcid.org/0009-0001-6001-2711
Ehsan FarhadiDepartment of Neurosurgery, Saveh University of Medical Science, Saveh, Markazi, Iran.
Mitra RahimiToxicological Research Center, Excellence Center & Department of Clinical Toxicology, School of Medicine, Shahid Beheshti University of Medical Science, Tehran, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMagnesium toxicity occurs mostly in patients with decreased renal function or in preeclamptic patients who underwent high-dose magnesium sulfate therapy. Iatrogenic injection of magnesium sulfate is a rare condition. Magnesium sulfate extensively influences heart, lung, and brain function. Therefore, it is crucial to manage magnesium sulfate overdose through intensive procedures if common treatments do not improve the patient's prognosis. Our paper focuses on a case study of a patient who overdosed on magnesium sulfate and was managed through hemodialysis. CASE PRESENTATION: A 50-year-old Iranian woman was admitted to the hospital, following the injection of two vials of magnesium sulfate (25 g each) by emergency medicine services mistakenly, instead of the vial of glucose. At the entrance of the emergency ward, she became pulseless, and they initiated cardiopulmonary resuscitation and intubation. Electrocardiogram and laboratory results showed hypermagnesemia. Primary supportive interventions-fluid therapy and calcium gluconate injections-were ineffective in halting the progression of the patient's symptoms. Therefore, we decided to initiate hemodialysis, which significantly improved the patient's symptoms. Consequently, she improved and was discharged from the intensive care unit and the hospital.

conclusionHypermagnesemia is a life-threatening and emergency condition that must be recognized and managed immediately. Hemodialysis should be considered promptly if basic supportive interventions such as calcium gluconate and fluid therapy are ineffective in treating hypermagnesemia.

Indexed as

Drug OverdoseMagnesium SulfateRenal DialysisFemaleHumansMiddle AgedTreatment OutcomeMagnesium SulfateCase reportHemodialysisMagnesium sulfate overdoseMagnesium toxicityMg toxicity

Identifiers

PMID40696447
PMCPMC12281940

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.