Evidence map›Paper›PMID 40696345›Full record

ArticleBMC public health2025

Associations of family support and loneliness with underlying depression in Chinese children and adolescents.

Gang Tian, Jinming Wang, Jialiang Zhu, Hengyu Hu, Yibin Hao

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Article in BMC public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

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5citing papers in PubMed
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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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5 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Gang TianHenan Province Hypertension Precision Prevention and Control Engineering Research Center, Henan Provincial People's Hospital, Zhengzhou University People's Hospital, Zhengzhou, Henan, 450003, China.
Jinming WangMedical Genetics Institute of Henan Province, Henan Provincial People's Hospital, Zhengzhou University People's Hospital, Zhengzhou, China.
Jialiang ZhuHenan Province Hypertension Precision Prevention and Control Engineering Research Center, Henan Provincial People's Hospital, Zhengzhou University People's Hospital, Zhengzhou, Henan, 450003, China.
Hengyu HuDepartment of Nursing, Henan Provincial Key Medicine Laboratory of Nursing, Henan Provincial People's Hospital, Zhengzhou University People's Hospital, Zhengzhou, Henan, China.
Yibin HaoHenan Province Hypertension Precision Prevention and Control Engineering Research Center, Henan Provincial People's Hospital, Zhengzhou University People's Hospital, Zhengzhou, Henan, 450003, China. haoyibin0708@163.com.

Funding

Henan Provincial Key R&D Special Project 231111313400
6 · The paper itself

Abstract

objectiveThis study aimed to examine whether loneliness mediate associations of family support with depression and the extent of interaction of family support and loneliness with depression in children and adolescents.

methodsThere were 2755 children and adolescents aged 18 and below from the China Family Panel Studies (CFPS) that participated in our study. Depression in children and adolescents was assessed by the Center for Epidemiologic Studies Depression Scale (CES-D). Data were analyzed using logistic regression models, mediation analysis models and the interaction effect models.

resultsOf the 2,755 children and adolescents, 848 (30.8%) reported feelings of loneliness and 2,452 (88.7%) reported feelings of depression. The results of the multivariate logistic regression analysis indicated that, in comparison to children and adolescents who reported having family support, those who lacked such support exhibited a higher probability of experiencing loneliness (odds ratio (OR) = 1.668, 95% confidence interval (CI): (1.318-2.111) and depression (OR, 95%CI = 2.267, 1.402-3.664). The results of the mediation analysis indicated that loneliness exerted a partial mediating effect on the relationship between family support and depression (β=-0.087, P < 0.001), with a mediation proportion of 33.21%. No significant multiplicative or additive interactions were observed between family support and loneliness on depression.

conclusionThe findings indicate that family support exerts a direct and indirect influence on depression, mediated by loneliness. The results suggest that parents should provide more support to children and adolescents to mitigate the risk of loneliness and underlying depression.

Indexed as

DepressionFamily RelationsLonelinessSocial SupportAdolescentChildChinaEast Asian PeopleFamily SupportFemaleHumansMaleChildren and adolescentsDepressionFamily supportInteractionLonelinessMediation

Identifiers

PMID40696345
PMCPMC12281704

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.