Evidence map›Paper›PMID 40696333›Full record

SynthesisBMC surgery2025

Association between thickness of subcutaneous fat and incisional surgical site infection following appendectomy: a systematic review and meta-analysis on observational studies.

Mansour Bahardoust, Yasaman Asadi Kalbibaki, Sara Shiraghaie, Shabnam Rashidi, Mohammadsadra Shamohammadi, Ali Hashemi Kiapay, Meisam Haghmoradi, Babak Goodarzy, Adnan Tizmaghz

Abstract readSystematic ReviewMeta-Analysis
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in BMC surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Mansour Bahardoust *Department of Epidemiology, School of Public Health, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Yasaman Asadi KalbibakiFaculty of Medicine, Isfahan University of Medical Sciences, Tehran, Iran.
Sara Shiraghaie *School of Medicine, Iran University of Medical Sciences, Tehran, Iran.
Shabnam RashidiMedical University of Lublin, Lublin, Poland.
Mohammadsadra ShamohammadiGastrointestinal and Liver Diseases Research Center, Iran University of Medical Sciences, Tehran, Iran.
Ali Hashemi KiapayResident of Surgery, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Meisam HaghmoradiDepartment of Orthopedic Surgery, Urmia University of Medical Sciences, Urmia, Iran.
Babak GoodarzySchool of Medicine, Iran University of Medical Sciences, Tehran, Iran. Babakgoodarzydvm@gmail.com.
Adnan TizmaghzDepartment of General Surgery, School of Medicine, Firoozabadi Hospital, Iran University of Medical Sciences, Tehran, Iran. adnan_ti@yahoo.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe relationship between thickness of subcutaneous fat (TSF) and surgical site infection (SSI), as one of the most common complications after appendectomy, has been inconsistent in different studies, which may be due to the low power of these studies. This meta-analysis aimed to investigate the relationship between SSI and TSF after open surgery (OS) and laparoscopic surgery (LS) in patients with appendicitis.

methodsPubMed, Embase, Scopus, Google Scholar, and Web of Science databases were searched based on mesh terms to find relevant studies from the beginning of 2000 to 2024. The mean TSF during surgery was defined as exposure, and SSI after OS or laparoscopy appendectomy was defined as an outcome. The heterogeneity between studies was assessed using Cochran's Q and I2 tests. Meta-regression was employed to manage the heterogeneity. Nine studies, including 4,439 patients, were included.

resultsThe pooled estimate from nine studies indicated that an increase in TSF was significantly associated with an increased risk of SSI(OR: 1.32, 95% CI: 1.12, 1.52, I

conclusionTSF was significantly associated with an increased risk of SSI after OS, while it was not significantly associated with an increased risk of SSI in laparoscopically operated patients. Considering TSF during surgery to choose the appropriate surgical method and post-treatment care can help prevent and reduce the risk of SSI after appendectomy.

Indexed as

AppendectomySubcutaneous FatSurgical Wound InfectionAppendicitisHumansLaparoscopyObservational Studies as TopicRisk FactorsAppendectomySubcutaneous fatSurgerySurgical site infectionThickness

Identifiers

PMID40696333
PMCPMC12281778

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.