Evidence map›Paper›PMID 40696276›Full record

ArticleBMC plant biology2025

Identification of a new QTL associated to reduced quinolizidine alkaloid content in white lupin (Lupinus albus, L.) and development of ultra-low alkaloid recombinants by stacking with the pauper allele.

András Patyi, Miriam Kamp, Christine Arncken, Elisa Biazzi, Michał Książkiewicz, Monika M Messmer, Michael Schneider, Aldo Tava, Mariateresa Lazzaro

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Article in BMC plant biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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2citing papers in PubMed
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1 · What the graph read from it

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3 · Its place in the literature

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2 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

András PatyiDepartment of Crop Sciences, Research Institute of Organic Agriculture (FiBL), Ackerstrasse 113, Frick, 5070, Switzerland. andras.patyi@fibl.org.
Miriam KampGetreidezüchtung Peter Kunz (gzpk), Seestrasse 6, Feldbach, 8714, Switzerland.
Christine ArnckenDepartment of Crop Sciences, Research Institute of Organic Agriculture (FiBL), Ackerstrasse 113, Frick, 5070, Switzerland.
Elisa BiazziCREA-Research Centre for Animal Production and Aquaculture, Viale Piacenza 29, Lodi, 26900, Italy.
Michał KsiążkiewiczInstitute of Plant Genetics, Polish Academy of Sciences, Strzeszyńska 34, Poznań, 60-479, Poland.
Monika M MessmerDepartment of Crop Sciences, Research Institute of Organic Agriculture (FiBL), Ackerstrasse 113, Frick, 5070, Switzerland.
Michael SchneiderDepartment of Crop Sciences, Research Institute of Organic Agriculture (FiBL), Ackerstrasse 113, Frick, 5070, Switzerland.
Aldo TavaCREA-Research Centre for Animal Production and Aquaculture, Viale Piacenza 29, Lodi, 26900, Italy.
Mariateresa LazzaroDepartment of Crop Sciences, Research Institute of Organic Agriculture (FiBL), Ackerstrasse 113, Frick, 5070, Switzerland.

Funding

Bundesamt für Landwirtschaft 2020/51European Commission 101000383Staatssekretariat für Bildung, Forschung und Innovation 101059872
6 · The paper itself

Abstract

backgroundWhite lupin (Lupinus albus, L.) is a grain legume cultivated for its high agronomic and nutritional potential, despite the accumulation of bitter and potentially harmful to health quinolizidine alkaloids (QA) in the grain. Modern sweet (i.e. low alkaloid content) varieties exist, which are exploiting different recessive mutations responsible for the desired low QA chemotype. The most widely used QA-reducing determinant, pauper, has been recently identified enabling marker-assisted selection, but unstable QA content across growing seasons and environments remain a challenge in white lupin cultivation.

resultsThrough Bulked Segregant Analysis of an F

conclusionThe discovery of this novel locus and the development of associated PACE markers, potentially applicable for marker-assisted selection together with pauper (especially after farther validation in a larger panel of accessions), can enhance the improvement of white lupin through the development of new varieties with very low and stable alkaloid content based on stacked allele recombinants. This can help to increase the cultivation of this useful yet underutilised crop and its use for human nutrition.

Indexed as

AlkaloidsLupinusQuantitative Trait LociQuinolizidinesAllelesChromosome MappingQuinolizidine AlkaloidsAlkaloidsQuinolizidine AlkaloidsQuinolizidinesBulked Segregant analysis (BSA)PCR allelic competitive extension (PACE)Plant breedingQuantitative trait locus (QTL)Quinolizidine alkaloids (QA)White lupin

Identifiers

PMID40696276
PMCPMC12281768

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.