ArticleJournal of cellular and molecular medicine2025
Featured Immune Characteristics of Periodontitis and Primary Sjögren's Syndrome Revealed by Single-Cell Transcriptome Analyses.
Article in Journal of cellular and molecular medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
3 citing papers in PubMed.
- Molecular Insights into Oral Manifestations in Sjögren's Disease.International journal of molecular sciences · 2026Review
- Investigating conjunctival immune pathways in Sjögren and non-Sjögren disease associated dry eye.The ocular surface · 2026Article
- Featured Immune Characteristics of Periodontitis and Primary Sjögren's Syndrome Revealed by Single-Cell Transcriptome Analyses.Journal of cellular and molecular medicine · 2025Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Periodontitis (PD) and primary Sjögren's syndrome (pSS) are persistent inflammatory diseases that affect oral health, and numerous studies have uncovered phenotypic and intrinsic correlations between the two. However, a comprehensive and high-resolution analysis at the single-cell level has not been reported comparing the immune cell landscapes in PD and pSS. This study integrated single-cell transcriptome data from peripheral blood mononuclear cells (PBMCs) of healthy controls (HC), PD and pSS patients sourced from the NCBI and NGDC databases. The scRNA datasets were integrated, and cells were clustered using Seurat, with further subdivision of T/NK, myeloid cells and B cell subclusters. Next, NicheNetr was used to analyse the communication between myeloid cells and CD8
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Registered trials
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