ArticleEuropean radiology2026
Multiphase aortic valve calcium scoring on true-non-contrast and calcium-preserving spectral reconstructions using dual-source photon-counting detector CT.
Article in European radiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
objectivesThis study investigated differences between aortic valve calcium (AVC) scores derived from true non-contrast (TNC) and virtual-non-contrast reconstructions acquired with photon-counting detector CT (PCD-CT) and the impact of ECG-phase variability on AVC scores. MATERIALS AND
methodsA hundred patients undergoing PCD-CT for transcatheter aortic valve implantation (TAVI) planning were retrospectively analyzed. Scores were computed using the Agatston methodology for TNC and virtual-non-iodine (VNI) reconstruction at scanner-selected optimal phase (best) and a fixed ECG-phase (300 ms). For VNI reconstructions, additional phases from 150 ms to 450 ms with 50 ms increments were reconstructed. AVC scores of TNC
resultsTNC
conclusionVNI is a feasible alternative for AVC scoring but tends to overestimate compared to TNC. While phase-dependent variability in TNC underscores the need for standardization, further optimization of VNI is necessary for routine clinical use. KEY POINTS: Question What is the performance of AVC score calculation from virtual non-contrast images with PCD-CT and the impact of the reconstructed ECG-phase? Findings VNI reconstructions tend to overestimate the scores compared to non-enhanced acquisitions. ECG phase significantly impacts AVC scores for non-enhanced acquisitions and VNI reconstructions. Clinical relevance Utilizing VNI reconstructions to calculate AVC scores might reduce radiation dose, and understanding the influence of ECG-phase on these scores might improve reliability.
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