Evidence map›Paper›PMID 40696111›Full record

ArticleNPJ digital medicine2025

Re-identification of patients from imaging features extracted by foundation models.

Giacomo Nebbia, Sourav Kumar, Stephen Michael McNamara, Christopher Bridge, J Peter Campbell, Michael F Chiang, Naresh Mandava, Praveer Singh, Jayashree Kalpathy-Cramer

Abstract read
In one paragraph

Article in NPJ digital medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
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  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Giacomo NebbiaOphthalmology Department, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.
Sourav KumarOphthalmology Department, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.
Stephen Michael McNamaraOphthalmology Department, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.
Christopher BridgeMartinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, MA, USA.
J Peter CampbellMPH, Ophthalmology, Oregon Health & Science University, Portland, OR, USA.
Michael F ChiangNational Eye Institute, National Institutes of Health, Bethesda, MD, USA.
Naresh MandavaOphthalmology Department, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.
Praveer SinghOphthalmology Department, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.
Jayashree Kalpathy-CramerOphthalmology Department, University of Colorado Anschutz Medical Campus, Aurora, CO, USA. jayashree.kalpathy-cramer@cuanschutz.edu.

Funding

Colorado Clinical and Translational Sciences Institute (CCTSI)UM1TR004399 · NCATS · UNIVERSITY OF COLORADO DENVER · PI JANINE A HIGGINS, RONALD J. SOKOL · 2023 to 2026
$30.7M
Horizon 2020 101137074NCATS NIH HHS TR004399NCATS NIH HHS UM1 TR004399
6 · The paper itself

Abstract

Foundation models for medical imaging are a prominent research topic, but risks associated with the imaging features they can capture have not been explored. We aimed to assess whether imaging features from foundation models enable patient re-identification and to relate re-identification to demographic features prediction. Our data included Colour Fundus Photos (CFP), Optical Coherence Tomography (OCT) b-scans, and chest x-rays and we reported re-identification rates of 40.3%, 46.3%, and 25.9%, respectively. We reported varying performance on demographic features prediction depending on re-identification status (e.g., AUC-ROC for gender from CFP is 82.1% for re-identified images vs. 76.8% for non-re-identified ones). When training a deep learning model on the re-identification task, we reported performance of 82.3%, 93.9%, and 63.7% at image level on our internal CFP, OCT, and chest x-ray data. We showed that imaging features extracted from foundation models in ophthalmology and radiology include information that can lead to patient re-identification.

Identifiers

PMID40696111
PMCPMC12283961

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.