Evidence map›Paper›PMID 40696100›Full record

ArticleScientific reports2025

Effects of the combined letter fluency task on frontal cortex regional and dynamic oxygenation patterns.

Paweł Krukow, Natalia Kopiś-Posiej, Víctor Rodríguez-González, Michał Mazur, Carlos Gómez, Jesús Poza

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

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No citing paper in PubMed yet.

4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

6 authors.

Paweł KrukowDepartment of Clinical Neuropsychiatry, Medical University of Lublin, Ul. Głuska 1, Lublin, 20-439, Poland. pawel.krukow@umlub.pl.
Natalia Kopiś-PosiejDepartment of Experimental Psychology, Institute of Psychology, The John Paul II, Catholic University of Lublin, Lublin, Poland.
Víctor Rodríguez-GonzálezBiomedical Engineering Group, University of Valladolid, Valladolid, Spain.
Michał MazurDepartment of Clinical Neuropsychiatry, Medical University of Lublin, Ul. Głuska 1, Lublin, 20-439, Poland.
Carlos GómezBiomedical Engineering Group, University of Valladolid, Valladolid, Spain.
Jesús PozaBiomedical Engineering Group, University of Valladolid, Valladolid, Spain.

Funding

Uniwersytet Medyczny w Lublinie DS193
6 · The paper itself

Abstract

Verbal fluency tests (VFTs) are commonly used tasks for analyzing frontal cortex activation imagined by functional near-infrared spectroscopy (fNIRS). Some new VFT versions have been developed to strengthen the test's executive character. However, these modified tasks were not used to recognize whether they activate cortical areas significantly differently compared with typical tasks. We introduced a modified VFT version consisting of the necessity to produce words according to one phonemic criterion and exclude others according to another phonemic criterion to establish frontal cortex task-dependent hemodynamic activity for the proposed new task. The analysis was conducted by comparison with a typical initial letter fluency task in a group of 35 students. Behavioral results showed between-tasks differences in productivity during the initial phase of performance. Increased oxygenated hemoglobin (oxy-Hb) concentration in lateral and frontopolar regions was noted in both analyzed tasks, but oxy-Hb suppression has been observed in the middle/superior frontal cortex only for the new one. Such an arrangement of selective metabolic activation and inactivation suggests that the brain's adaptation to increased processing demands may consist of restraining the oxygen intake of the neuronal region, which activity is not necessary to perform a task.

Indexed as

Frontal LobeOxygenVerbal BehaviorAdultBrain MappingFemaleHumansMaleOxyhemoglobinsSpectroscopy, Near-InfraredYoung AdultOxygenOxyhemoglobinsfNIRSPrefrontal cortexSelective InhibitionTask difficultyVerbal fluency

Identifiers

PMID40696100
PMCPMC12284028

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LicenceCC BY-NC-ND
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.