Evidence map›Paper›PMID 40696084›Full record

ArticleEJNMMI radiopharmacy and chemistry2025

Multifactorial analysis of radiochemical purity in high-activity

William Hunt, Mathew Long, Usama Kamil, Sunil Kellapatha, Wayne Noonan, Peter D Roselt, Nathan Papa, Brittany Emmerson, Michael S Hofman, Mohammad B Haskali

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in EJNMMI radiopharmacy and chemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. GMP-compliant automated synthesis and quality control of [EJNMMI radiopharmacy and chemistry · 2026
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

William HuntDepartment of Radiopharmaceutical Sciences, Cancer Imaging, The Peter MacCallum Cancer Centre, Melbourne, VIC, 3000, Australia.
Mathew LongDepartment of Radiopharmaceutical Sciences, Cancer Imaging, The Peter MacCallum Cancer Centre, Melbourne, VIC, 3000, Australia.
Usama KamilDepartment of Radiopharmaceutical Sciences, Cancer Imaging, The Peter MacCallum Cancer Centre, Melbourne, VIC, 3000, Australia.
Sunil KellapathaDepartment of Radiopharmaceutical Sciences, Cancer Imaging, The Peter MacCallum Cancer Centre, Melbourne, VIC, 3000, Australia.
Wayne NoonanDepartment of Radiopharmaceutical Sciences, Cancer Imaging, The Peter MacCallum Cancer Centre, Melbourne, VIC, 3000, Australia.
Peter D RoseltDepartment of Radiopharmaceutical Sciences, Cancer Imaging, The Peter MacCallum Cancer Centre, Melbourne, VIC, 3000, Australia.
Nathan PapaSchool of Public Health and Preventive Medicine, Monash University, Melbourne, VIC, 3004, Australia.
Brittany EmmersonDepartment of Radiopharmaceutical Sciences, Cancer Imaging, The Peter MacCallum Cancer Centre, Melbourne, VIC, 3000, Australia.
Michael S HofmanThe Sir Peter MacCallum Department of Oncology, The University of Melbourne, Melbourne, VIC, 3000, Australia.
Mohammad B HaskaliDepartment of Radiopharmaceutical Sciences, Cancer Imaging, The Peter MacCallum Cancer Centre, Melbourne, VIC, 3000, Australia. mo.haskali@petermac.org.ORCID http://orcid.org/0000-0003-3084-2084

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLutetium-177 (

resultsWe analyzed 355 clinical batches of [

conclusionThis comprehensive analysis reveals that hospital-based production can be automized resulting in high-quality and efficient multi-dose production. Small differences in radiochemical purity of

Indexed as

Carrier-added lutetium-177DOTATATEHigh-activity productionLutetium-177 theranosticsNon-carrier-added lutetium-177PSMA-617PSMA-I&TQuality controlRadiochemical purityRadiolysis

Identifiers

PMID40696084
PMCPMC12283506

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.