Evidence map›Paper›PMID 40696038›Full record

ArticleArchives of gynecology and obstetrics2025

Combined transcervical radiofrequency ablation and hysteroscopic myomectomy: expanding treatment to diverse fibroid types.

Elvin Piriyev, Angelika Dieter, Sven Schiermeier, Stefan Peter Renner, Thomas Römer

Abstract readMulticenter Study
In one paragraph

Article in Archives of gynecology and obstetrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Contemporary Management of Uterine Fibroids.Journal of clinical medicine · 2026
    Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Elvin PiriyevChair of Obstetrics and Gynecology, University Witten-Herdecke, Germany, Alfred-Herrhausen-Straße 50, 5093358455, Witten, Germany. piriyev.elvins@gmail.com.ORCID 0000-0002-2544-4770
Angelika DieterDepartment of Gynecology and Obstetrics, Boeblingen Clinic, Hospital Sindelfingen-Böblingen, Böblingen, Germany.
Sven SchiermeierChair of Obstetrics and Gynecology, University Witten-Herdecke, Germany, Alfred-Herrhausen-Straße 50, 5093358455, Witten, Germany.
Stefan Peter RennerDepartment of Gynecology and Obstetrics, Boeblingen Clinic, Hospital Sindelfingen-Böblingen, Böblingen, Germany.
Thomas RömerDepartment of Obstetrics and Gynecology, Academic Hospital Cologne Weyertal, Cologne, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionUterine fibroids are highly prevalent and often symptomatic, leading to abnormal uterine bleeding (AUB) and impaired quality of life. While hysteroscopic myomectomy (HSC) is the gold-standard treatment for submucosal fibroids, it is limited in addressing deeper lesions. Transcervical radiofrequency ablation (TFA) offers a minimally invasive alternative for intramural and transmural fibroids. This study evaluated the safety and effectiveness of combining TFA with HSC in a single session compared to HSC alone. STUDY

designWe conducted a retrospective multicenter analysis of 127 women with symptomatic fibroids and AUB. Patients underwent either combined TFA + HSC (n = 75) or HSC alone (n = 52). Outcomes included intraoperative bleeding, complications, and symptom improvement.

resultsThe combined group treated a broader range of fibroid types (FIGO 0-6) and larger fibroids (mean size 2.86 cm vs. 2.23 cm; p = 0.0013). Intraoperative bleeding was significantly lower in the combined group (0% vs. 9.6%; p = 0.0102), with no increase in total complication rates (8% vs. 15%; p = 0.2512). Among patients with follow-up data, 85.1% reported symptom improvement after combined treatment.

conclusionCombining TFA with hysteroscopic myomectomy is a safe and effective approach that expands the range of treatable fibroids, reduces intraoperative bleeding, and maintains high patient satisfaction. This integrated strategy offers advantages in tissue diagnosis, potential cost savings, and uterine preservation, making it a valuable addition to minimally invasive fibroid management.

Indexed as

HysteroscopyLeiomyomaRadiofrequency AblationUterine MyomectomyUterine NeoplasmsAdultBlood Loss, SurgicalCombined Modality TherapyFemaleHumansMiddle AgedRetrospective StudiesTreatment OutcomeUterine HemorrhageAUBFibroidHSCOperative hysteroscopyTFA

Identifiers

PMID40696038
PMCPMC12414017

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.