ArticleCommunications biology2025
Mapping the microstructure of human cerebral cortex in vivo with diffusion MRI.
Article in Communications biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Gray Matter Morphological Networks are Associated with Neurobiological Features, Cognitive Status and Clinical Recovery in Traumatic Brain Injury.medRxiv : the preprint server for health sciences · 2026Article
- MV-ComBat and MV-CovBat: Multivariate Frameworks for Joint Harmonization of Multi-Metric Neuroimaging Data.bioRxiv : the preprint server for biology · 2026Article
- An Open, Fully-processed, Longitudinal Data Resource to Study Brain Development and Transdiagnostic Executive Function.bioRxiv : the preprint server for biology · 2025Article
- Estimating Brain Similarity Networks With Diffusion MRI.Human brain mapping · 2025Article
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Authors and funding
5 authors.
Funding
Abstract
Despite advances in diffusion MRI, which have led to remarkable progress in mapping white matter of the living human brain, our understanding of cerebral cortical microstructure in vivo and its relationship to macrostructure, myeloarchitecture, cytoarchitecture, chemoarchitecture, metabolism, and function lag far behind. We present neuromaps of 21 microstructural metrics derived from diffusion tensor, diffusion kurtosis, mean apparent propagator, and neurite orientation dispersion and density imaging of the young adult cerebral cortex. These 21 metrics are explained by four composite factors that correspond to diffusion kurtosis (intracellular volume fraction/neurite density), isotropic diffusion (free water fraction), heterogenous diffusion (extracellular volume fraction) and diffusion anisotropy (neurite orientation dispersion). We demonstrate how cortical microstructure follows cytoarchitectural and laminar differentiation, aligns with the macroscale sensory-fugal and sensorimotor-association axes, and contributes to functional brain networks, neural oscillatory dynamics, neurotransmitter receptor/transporter distributions, and cognition and behavior.
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Registered trials
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