Evidence map›Paper›PMID 40696008›Full record

ArticleMycopathologia2025

Topical Luliconazole Treatment for Hyperkeratotic Tinea Pedis.

Sayaka Ohara, Hiromitsu Noguchi, Tadahiko Matsumoto, Daiki Hayashi, Kayo Kashiwada-Nakamura, Masahide Kubo, Rui Kano, Satoshi Fukushima

Abstract read
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In one paragraph

Article in Mycopathologia, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Sayaka OharaDepartment of Dermatology, National Defense Medical College, Saitama, Japan.
Hiromitsu NoguchiNoguchi Dermatology Clinic, 964-1 Uejima, Kashima-machi, Kamimashiki-gun, Kumamoto, 861-3106, Japan. derma@nogcli.jp.ORCID http://orcid.org/0000-0003-4993-304X
Tadahiko MatsumotoNoguchi Dermatology Clinic, 964-1 Uejima, Kashima-machi, Kamimashiki-gun, Kumamoto, 861-3106, Japan.
Daiki HayashiDepartment of Dermatology and Plastic Surgery, Faculty of Life Sciences, Kumamoto University Kumamoto, Kumamoto, Japan.
Kayo Kashiwada-NakamuraDepartment of Dermatology and Plastic Surgery, Faculty of Life Sciences, Kumamoto University Kumamoto, Kumamoto, Japan.
Masahide KuboNoguchi Dermatology Clinic, 964-1 Uejima, Kashima-machi, Kamimashiki-gun, Kumamoto, 861-3106, Japan.
Rui KanoTeikyo University Institute of Medical Mycology (TIMM), Tokyo, Japan.
Satoshi FukushimaDepartment of Dermatology and Plastic Surgery, Faculty of Life Sciences, Kumamoto University Kumamoto, Kumamoto, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chronic hyperkeratotic tinea pedis is a treatment-resistant infection. We evaluated the efficacy of a 3-month course of topical 1% luliconazole in 21 hyperkeratotic tinea pedis patients. The diagnosis was confirmed through microscopy and culture. The lesion area was assessed monthly using a software program. Clinical responses were classified into five categories from "cured" to "no change." Among the isolates, one terbinafine-resistant T. rubrum strain was detected. The mean lesion area decreased significantly over 3 months, with an average improvement rate of 94.1% ± 12.7% and a cure rate of 61.9%. The mean amount of luliconazole used per foot was 27.5 ± 9.7 g monthly. The resistant case showed a partial improvement with topical luliconazole and was successfully treated with oral fosravuconazole. These findings suggest that 1% topical luliconazole is effective for treating hyperkeratotic tinea pedis.

Indexed as

Antifungal AgentsImidazolesTinea PedisAdministration, TopicalAdolescentAdultAgedArthrodermataceaeFemaleHumansMaleMiddle AgedTreatment OutcomeYoung AdultAntifungal AgentsImidazolesluliconazoleFosravuconazoleHyperkeratotic tinea pedisLuliconazoleTerbinafine-resistance

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.