Evidence map›Paper›PMID 40695312›Full record

ArticleAddiction (Abingdon, England)2025

Fatal drug overdoses in healthcare workers: A thematic framework analysis of coroner reports.

Thikra Algahtani, Siobhan Gee, Aminah Shah, Bryn D Williams, Hayley C Gorton, Sarah Welch, Caroline S Copeland

Abstract read
In one paragraph

Article in Addiction (Abingdon, England), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Thikra AlgahtaniCentre for Pharmaceutical Medicine Research, Institute of Pharmaceutical Science, King's College London, London, UK.
Siobhan GeePharmacy Department, South London and Maudsley NHS Foundation Trust, London, UK.
Aminah ShahCentre for Pharmaceutical Medicine Research, Institute of Pharmaceutical Science, King's College London, London, UK.
Bryn D WilliamsDepartment of Anaesthetics, Royal Free Hospital, London, UK.
Hayley C GortonPharmacy School, Aston University, Birmingham, UK.
Sarah WelchRetired Consultant Addictions Psychiatrist.
Caroline S CopelandCentre for Pharmaceutical Medicine Research, Institute of Pharmaceutical Science, King's College London, London, UK.ORCID https://orcid.org/0000-0002-4462-1402

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

aimsHealthcare workers face specific vulnerabilities for drug overdose due to their unique access to medications, clinical knowledge and work-related stress. This study aimed to understand the characteristics of fatal overdoses in healthcare workers with a view to providing guidance for preventative strategies. DESIGN, SETTING AND CASES: We retrospectively identified cases in England, Wales and Northern Ireland reported to the National Programme on Substance Use Mortality between 2000 and 2022 where decedents were working or studying within a healthcare setting at the time of their death or had previously worked in healthcare. MEASUREMENTS: Quantitative analyses were conducted to report summary demographics of decedents, the circumstances of deaths and the drugs involved. A qualitative thematic framework analysis was performed to identify and explore factors that may contribute to fatal drug overdose in healthcare professionals.

findingsIn the identified cases, doctors were the most represented profession (48% of cases, n = 28/58) with opioids the drug class most often implicated in causing death (43% of cases, n = 25/58). Whilst there was scant evidence of recreational drug use in the identified cases (n = 3), hospital-only medications prominently featured [propofol in 29% (n = 17/58); midazolam in 10% (n = 6/58); neuromuscular blocking agents in 9% (n = 5/58)]. Qualitative analysis identified seven themes including accessing drugs from the workplace, use of skills and/or equipment for intravenous drug administration, obtainment of private prescriptions, diagnosed mental health conditions, recent events likely to have negatively impacted mental health, chronic pain and self-medicating and history of substance use disorder and/or overdose.

conclusionsThe characteristics of fatal drug overdoses among healthcare workers in England, Wales and Northern Ireland appear to differ from those observed in the overall population of people who use drugs in the UK. To prevent such deaths, it is important that healthcare workers can access bespoke care and support tailored to the specific challenges that they face.

Indexed as

Drug OverdoseHealth PersonnelAdultCoroners and Medical ExaminersEnglandFemaleHumansMaleMiddle AgedNorthern IrelandRetrospective StudiesWalesYoung Adultdrug‐related deathdrug toxicityhealthcare workersmental healthoverdosesuicide

Identifiers

PMID40695312
PMCPMC12529239

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.