Evidence map›Paper›PMID 40694836›Full record

ArticleJMIR research protocols2025

Resilience Coaching for Adolescent Chronic Musculoskeletal Pain: Protocol for a Pilot Randomized Controlled Trial of Promoting Resilience in Stress Management (PRISM).

Sabrina Gmuca, Mackenzie McGill, Nellie Butler, Rui Xiao, Peter F Cronholm, Jami F Young, Tonya M Palermo, Pamela F Weiss, Abby R Rosenberg

Registry-linked trialAbstract readClinical Trial Protocol
In one paragraph

Article in JMIR research protocols, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05834725 (A Pilot Randomized Controlled Trial of Resilience Coaching for Adolescents With Chronic Musculoskeletal Pain), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05834725 nacompletednot on this map

A Pilot Randomized Controlled Trial of Resilience Coaching for Adolescents With Chronic Musculoskeletal Pain

TypeinterventionalSponsorChildren's Hospital of PhiladelphiaRan2023 to 2026Enrolled260ConditionsPain, Chronic, Pain Syndrome, PsychologicalArmsPromoting Resilience in Stress Management, Usual Care
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Sabrina GmucaDivision of Rheumatology, Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, PA, United States.ORCID 0000-0003-3533-5698
Mackenzie McGillDivision of Rheumatology, Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, PA, United States.ORCID 0000-0001-6209-4733
Nellie ButlerDivision of Rheumatology, Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, PA, United States.ORCID 0009-0001-8786-3516
Rui XiaoDepartment of Biostatistics, Epidemiology and Informatics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States.ORCID 0000-0002-2727-8171
Peter F CronholmPerelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States.ORCID 0000-0003-2570-7056
Jami F YoungPolicyLab, Children's Hospital of Philadelphia, Philadelphia, PA, United States.ORCID 0000-0002-7488-5097
Tonya M PalermoDepartment of Anesthesiology and Pain Medicine, School of Medicine, University of Washington, Seattle, WA, United States.ORCID 0000-0001-6036-6715
Pamela F WeissDivision of Rheumatology, Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, PA, United States.ORCID 0000-0002-9724-0443
Abby R RosenbergDepartment of Supportive Oncology, Division of Pediatric Palliative Care, Dana-Farber Cancer Institute, Boston, MA, United States.ORCID 0000-0002-7608-607X

Funding

A Pilot Randomized Controlled Trial of Resilience Coaching for Adolescents with Chronic Musculoskeletal PainK23AR081409 · NIAMS · CHILDREN'S HOSP OF PHILADELPHIA · PI SABRINA ANDREA GMUCA · 2022 to 2026
$955k
Mentoring and Patient Oriented Research in Juvenile SpondyloarthritisK24AR078950 · NIAMS · CHILDREN'S HOSP OF PHILADELPHIA · PI Pamela Fitch Weiss · 2022 to 2026
$664k
NIAMS NIH HHS K23 AR081409NIAMS NIH HHS K24 AR078950
6 · The paper itself

Abstract

backgroundLevels of self-perceived psychological resilience are low to moderate among youth with chronic musculoskeletal pain (CMP). Furthermore, resilience has been associated with symptom severity in CMP. Resilience coaching programs may therefore be of benefit in the nonpharmacologic management of adolescent CMP and may serve as an adjunctive way to access mental health services in an approachable and affordable way.

objectiveThe main goal of the study is to assess the feasibility, acceptability, and preliminary efficacy of the resilience coaching program called Promoting Resilience in Stress Management (PRISM) and to obtain the data needed to plan a larger trial.

methodsThe Resilience Coaching for Adolescents with Chronic Musculoskeletal Pain pilot study is an investigator initiated, 2-arm, randomized controlled trial (RCT) of PRISM in the interdisciplinary management of CMP among adolescents. The study will compare usual care versus PRISM+usual care among adolescents newly diagnosed with CMP in the outpatient setting. One caregiver per patient will also be enrolled. The control group will receive usual care with no specific intervention. The treatment arm will receive PRISM, which is a remotely delivered, 1-on-1resilience coaching program, consisting of 4 required skill-based sessions and an optional final session. Sessions will be delivered every 1-2 weeks, lasting about 3 months in total. The primary outcome is the Functional Disability Inventory (FDI) score at 3 months postrandomization. The secondary objectives are to evaluate potential patient- and caregiver-level moderators of PRISM and identify facilitators of and barriers to engagement in PRISM. The estimated sample size is 65 patient-caregiver dyads per group, for a total of 130 dyads.

resultsThe trial is currently open. Initial Institutional Review Board approval was obtained on April 4, 2023, and protocol version 4 was amended on January 14, 2025. Recruitment began on May 8, 2023, and recruitment is anticipated to be completed on August 1, 2025.

conclusionsResilience coaching has demonstrated excellent feasibility, acceptability, and efficacy in teenagers with chronic illness; however, evidence to support its use in adolescent CMP is lacking. Resilience coaching has the potential to improve patient outcomes in this population. This pilot RCT will demonstrate acceptability, feasibility, and preliminary efficacy and reveal critical barriers to and facilitators of engagement. This will inform a larger multisite trial to evaluate the definitive efficacy of the intervention.

trial registrationClinicalTrials.gov NCT05834725; https://clinicaltrials.gov/study/NCT05834725. INTERNATIONAL REGISTERED REPORT IDENTIFIER (IRRID): DERR1-10.2196/73385.

Indexed as

Chronic PainMentoringMusculoskeletal PainResilience, PsychologicalStress, PsychologicalAdolescentFemaleHumansMalePilot ProjectsRandomized Controlled Trials as Topicchronic musculoskeletal painchronic painpediatric rheumatologypilot studyresilience

Identifiers

PMID40694836
PMCPMC12326160

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.