Evidence map›Paper›PMID 40694387›Full record

Trial reportJournal of clinical psychology2025

Can Interpersonal Trust Predict and Account for Symptom Change During Group Cognitive Processing Therapy for PTSD? An Investigation of the Iterated Trust Game.

M Wright Williams, Christopher Hunt, David P Graham, Matt Estey, Lia Smith, Katherine McCurry, Brooks King-Casas, Pearl Chiu

Abstract readClinical TrialComparative Study
In one paragraph

Trial report in Journal of clinical psychology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

M Wright WilliamsMichael E. DeBakey Veterans Affairs Medical Center, Houston, Texas, USA.
Christopher HuntUniversity of California San Diego, San Diego, California, USA.ORCID 0000-0002-1123-1440
David P GrahamMichael E. DeBakey Veterans Affairs Medical Center, Houston, Texas, USA.
Matt EsteyMenninger Clinic, Houston, Texas, USA.
Lia SmithThe University of Houston, Houston, Texas, USA.
Katherine McCurryResearch Service Line, Salem VA Medical Center, Salem, Virginia, USA.ORCID 0000-0001-6921-7636
Brooks King-CasasResearch Service Line, Salem VA Medical Center, Salem, Virginia, USA.
Pearl ChiuResearch Service Line, Salem VA Medical Center, Salem, Virginia, USA.

Funding

Neurobehavioral metrics for the assessment and treatment of depressionR01MH087692 · NIMH · VIRGINIA POLYTECHNIC INST AND ST UNIV · PI CHIU, PEARL H · 2010 to 2014
$1.6M
NIMH NIH HHS R01 MH087692RRD VA I01 RX000522This study was supported by the VA Rehabilitation Research and Development branch (Grant I01 RX000522, awarded to WW; Grant D7030R, awarded to BKC) and the National Institutes of Mental Health (Grant MH087692, awarded to PC). CH's contributions to this article were supported by a fellowship from VA Office of Academic Affiliations and the Center of Excellence for Stress and Mental Health at the VA San Diego.
6 · The paper itself

Abstract

objectiveGroup cognitive processing therapy (GCPT) is frequently utilized to treat PTSD within the VA healthcare system, but its mechanisms are not well understood. Interpersonal trust could be an important change process in GCPT given its relevance to group-based therapy and its role in CPT, but self-report measures are inadequate for capturing the dynamic interplay that defines interpersonal trust. Here, we examined the degree to which interpersonal could predict and account for PTSD symptom change in GCPT using the iterated trust game (ITG)-a behavioral task used to approximate real-world trust behavior.

methodsParticipants were Veterans with PTSD who participated in an effectiveness trial comparing a 12-week course of GCPT (n = 37) to a treatment-as-usual (TAU) waitlist condition (n = 23) of equivalent length. Both groups completed the ITG and measures of PTSD before and after treatment as well as a pencil-paper measure of interpersonal trust before treatment. Participants in GCPT completed measures of PTSD severity, group relationship quality, and therapist relationship quality at each treatment session.

resultsPre-post changes in ITG-measured trust behavior did not differ between GCPT and TAU (p = 0.075). However, improvements in ITG scores partially accounted for decreased PTSD symptoms in GCPT, as demonstrated by a more modest change in PTSD symptoms when ITG was in, b = -5.95, p = 0.032, versus not in the model, b = -9.05, p = 0.001. Additionally, higher ITG scores, but not self-reported trust, predicted steeper reductions in PTSD symptoms, b = -0.50, p = 0.042, and improvements in group relationship quality, b = 0.28, p = 0.037, across GCPT sessions.

conclusionsInterpersonal trust improvement may predict and account for symptom change in GCPT. Targeting interpersonal trust during GCPT could render the treatment more effective.

Indexed as

Cognitive Behavioral TherapyPsychotherapy, GroupStress Disorders, Post-TraumaticTrustVeteransAdultFemaleGames, ExperimentalHumansInterpersonal RelationsMaleMiddle AgedTreatment OutcomeYoung Adultcognitive processing therapygroup psychotherapyiterated trust gamePTSDtreatment mechanismstreatment prediction

Identifiers

PMID40694387
PMCPMC12501833

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.