SynthesisOrthopaedic surgery2025
Comparison of Unicompartmental Knee Arthroplasty Versus High Tibial Osteotomy for Medial Knee Osteoarthritis: An Updated Meta-Analysis of 56,000 Patients.
Synthesis in Orthopaedic surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
8 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- High tibial osteotomy versus unicompartmental knee arthroplasty for medial compartment knee osteoarthritis: a comprehensive meta-analysis with patient-specific stratification by age, BMI, and preoperative activity levels.BMC musculoskeletal disorders · 2026Pooled it
- Comparison of Unicompartmental Knee Arthroplasty Versus High Tibial Osteotomy for Medial Knee Osteoarthritis: An Updated Meta-Analysis of 56,000 Patients.Orthopaedic surgery · 2025Pooled it
- Selecting between UKA and HTO in the grey zone.Journal of orthopaedic translation · 2026Article
- Evolving Strategies for Knee Osteoarthritis: A Narrative Review of Integrated Rehabilitation, Pharmacologic, and Joint-Preserving Interventions.Medical science monitor : international medical journal of experimental and clinical research · 2026Review
- Implantable Shock Absorber: Breakthrough or Hype?Current reviews in musculoskeletal medicine · 2026Review
- Mid-Term Clinical Outcomes of Pullout Repair Combined with Osteochondral Autograft Transplantation for Medial Meniscus Posterior Root Tears with Focal Cartilage Defects: A Treatment-Stratified Cohort Study.Bioengineering (Basel, Switzerland) · 2026Article
- Reliable pain and function outcomes but limited sport performance after high tibial osteotomy for medial knee osteoarthritis in the grey zone between osteotomy and unicompartmental replacement.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2026Article
- Comparative efficacy of total knee arthroplasty versus unicompartmental knee arthroplasty in obese patients with medial knee osteoarthritis.Frontiers in medicine · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors.
Funding
Abstract
Osteoarthritis (OA) is a prevalent degenerative joint disease primarily affecting hip and knee joints, with an estimated 300 million cases globally. This study is crucial as it provides an updated, comprehensive comparison of unicompartmental knee arthroplasty (UKA) and high tibial osteotomy (HTO) for treating medial knee osteoarthritis, offering valuable insights into their relative effectiveness. The findings aim to inform clinical decision-making and improve patient outcomes by identifying the superior treatment option. A comprehensive search was conducted across PubMed, Cochrane Library, and Google Scholar until August 1, 2024. Statistical analysis used Review Manager 5.4 with a random-effects model, risk ratio (RR), and mean differences (MD) with 95% confidence intervals (CI) for the dichotomous and continuous outcomes, respectively. The Newcastle-Ottawa Scale was used for quality assessment, and funnel plots were used to analyze publication bias. GRADE assessment was done to gauge the certainty of the evidence. Thirty-nine studies, involving a total of 56,686 patients, were evaluated for comparison. UKA significantly reduced the complications (RR = 0.37; 95% CI: [0.25, 0.54]; p < 0.0001; I
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.