Evidence map›Paper›PMID 40694334›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2025

The Gln-rich protein twip1 promotes high-density {110} twins formation in the shell of the limpet

Sicheng Li, Xinlu Liu, Zehua Zheng, Keisuke Oshima, Lingxiao Zhu, Yugo Kato, Lumi Negishi, Hitoshi Kurumizaka, Taiga Okumura, Koji Nagata and 2 more

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Sicheng LiDepartment of Applied Biological Chemistry, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Tokyo 113-8657, Japan.ORCID 0009-0003-0825-4902
Xinlu LiuDepartment of Applied Biological Chemistry, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Tokyo 113-8657, Japan.ORCID 0009-0002-6630-1618
Zehua ZhengBone Marrow Transplantation Center, The First Affiliated Hospital & Liangzhu Laboratory, Zhejiang University School of Medicine, Hangzhou 311121, China.ORCID 0000-0002-3615-1690
Keisuke OshimaDepartment of Applied Biological Chemistry, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Tokyo 113-8657, Japan.
Lingxiao ZhuLiangzhu Laboratory, Zhejiang University, Hangzhou 311121, China.
Yugo KatoDepartment of Applied Biological Chemistry, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Tokyo 113-8657, Japan.ORCID 0000-0002-4334-962X
Lumi NegishiInstitute for Quantitative Biosciences, The University of Tokyo, Tokyo 113-8657, Japan.
Hitoshi KurumizakaInstitute for Quantitative Biosciences, The University of Tokyo, Tokyo 113-8657, Japan.ORCID 0000-0001-7412-3722
Taiga OkumuraDepartment of Earth and Planetary Science, Graduate School of Science, The University of Tokyo, Tokyo 113-0033, Japan.ORCID 0000-0001-5252-8622
Koji NagataDepartment of Applied Biological Chemistry, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Tokyo 113-8657, Japan.
Boaz PokroyDepartment of Materials Science and Engineering, Technion - Israel Institute of Technology, Haifa 32000, Israel.ORCID 0000-0003-0480-7250
Michio SuzukiDepartment of Applied Biological Chemistry, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Tokyo 113-8657, Japan.ORCID 0000-0001-6150-8957

Funding

Bank Discount Academic Chair N.A.Basis for Supporting Innovative Drug Discovery and Life Science Research JP24ama121009Environmental Restoration and Conservation Agency (ERCA) CN2201ISF-JSPS 172/21MEXT | Japan Society for the Promotion of Science (JSPS) 19H05771MEXT | Japan Society for the Promotion of Science (JSPS) 21K19020MEXT | Japan Society for the Promotion of Science (JSPS) 23H00339MEXT | Japan Society for the Promotion of Science (JSPS) 25H01449New Energy and Industrial Technology Development Organization (NEDO) JPNP22100161-0
6 · The paper itself

Abstract

Aragonite, a polymorph of calcium carbonate (CaCO

Indexed as

Animal ShellsCalcium CarbonateGastropodaProteinsAnimalsBiomineralizationCrystallizationCalcium CarbonateProteinsaragonite {110} twinsbiomineralizationlimpet SMPs

Identifiers

PMID40694334
PMCPMC12318190

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.