Evidence map›Paper›PMID 40694312›Full record

ArticleJournal of clinical monitoring and computing2026

Evaluating the efficacy of intraoperative NIRS cutoff values in detecting spinal cord ischemia during surgery.

Sebastian Zinn, Nia Joseph, Travis Stanley CreveCoeur, Roman M Sniecinski, Paul S García

Abstract read
In one paragraph

Article in Journal of clinical monitoring and computing, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Sebastian ZinnDepartment of Anesthesiology, Columbia University Medical Center, New York, USA. zinn@med.uni-frankfurt.de.ORCID 0000-0003-1052-3828
Nia JosephDepartment of Anesthesiology, Columbia University Medical Center, New York, USA.
Travis Stanley CreveCoeurDepartment of Neurosurgery, Columbia University Medical Center, New York, USA.
Roman M SniecinskiDepartment of Anesthesiology, Emory University, Atlanta, USA.
Paul S GarcíaDepartment of Anesthesiology, Columbia University Medical Center, New York, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeParalysis is a serious complication of surgeries that interferes with the blood supply of the anterior spinal cord, with rates of spinal cord injury (SCI) from approximately 1% in general spine surgeries to 4-40% following thoracoabdominal aortic aneurysm (TAAA) repair. Near-infrared spectroscopy (NIRS) provides a non-invasive, real-time method for monitoring tissue oxygenation, largely unaffected by anesthetics. Given the heightened risk of neurologic injury during TAAA repair, this procedure is used to evaluate the effectiveness of standard regional spinal oxygen saturation (rSpO₂) cutoff values in predicting neurological outcomes.

methodsThis retrospective study analyzed 25 patients undergoing open TAAA repair. NIRS data were recorded at the ischemic site and a reference location throughout surgery. Neurological outcomes were assessed postoperatively based on paralysis, hemiparesis, or extremity weakness. After excluding eight patients due to poor signal quality, 17 patients were included. NIRS values at six key time points were compared between outcome groups. Bayesian statistics assessed the relationship between significant NIRS "drops" (< 80% of baseline) and neurological outcomes.

resultsSeven patients exhibited new neurological deficits (4 temporary). No credible association was found between intraoperative NIRS drops and postoperative neurological outcomes at any analyzed time point. A moderate effect was observed at the end of surgery (Hedges' g = - 1.21), suggesting a potential difference between groups, although the Bayesian credible interval included zero (posterior mean = - 0.82, 94% HDI [- 1.8, 0.18]).

conclusionsIn this limited cohort, intraoperative NIRS cutoff values did not significantly correlate with postoperative neurological deficits following TAAA repair. Postoperative NIRS monitoring may be more informative for detecting spinal cord ischemia and preventing paralysis.

Indexed as

Monitoring, IntraoperativeSpinal Cord IschemiaAdultAgedAortic Aneurysm, ThoracicBayes TheoremFemaleHumansMaleMiddle AgedOxygenOxygen SaturationRetrospective StudiesSpectroscopy, Near-InfraredSpinal CordOxygenNear-infrared spectroscopyNeurological outcomesSpinal cord ischemiaThoracoabdominal aortic aneurysmTissue oxygenation monitoring

Identifiers

PMID40694312
PMCPMC13053335

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.