ArticleEuropean journal of nutrition2025
High dietary total energy intake and energy density are associated with girls' breast density during puberty.
Article in European journal of nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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5 authors.
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Abstract
purposeBreast density (BD) is an important risk factor for breast cancer (BC). Excessive caloric intake in adulthood is associated with an increased risk of BC and BD in adults. We aim to assess whether high total energy intake and energy density in the diet during puberty is associated with breast composition (% fibroglandular volume (%FGV) and absolute fibroglandular volume (AFGV) in girls two years after menarche onset independently of body size.
methodsLongitudinal study within the "Chilean Growth and Obesity Study". Total energy intake (TEI), dietary energy density (ED), and calories from foods with high energy density (FHED) were assessed in 369 girls by 24 h dietary recall (24 h), available from puberty until 2 years after menarche onset. Breast composition was measured through Dual Energy X-ray Absorptiometry.
resultsThe 17.1% of the girls were classified as obese. The mean reported of TEI was 1755 kcal/d (SD = 371 kcal), ED 1.03 kcal/g (SD = 0.18 kcal/g), and FHED 1042.2 kcal/d (SD = 294.7). The 4th quartiles of TEI and FHED were positively associated with %FGV (Q4 vs. Q1: ß = 0.08 (95%CI 0.02; 0.16) and ß = 0.10 (95%CI 0.03; 0.17), respectively). In the case of AFGV we observed a positive association between the 4th quartile of TEI, ED and FHED (Q4 vs. Q1: ß = 0.14 (95%CI 0.02; 0.26), 0.12 (95%CI 0.004; 0.24) and ß = 0.17 (95%CI 0.05; 0.29) respectively.
conclusionsThis is the first study to suggest an association between high energy dense foods and total energy intake during puberty and adolescent breast density. Further research is warranted to elucidate these associations across different life stages and underlying mechanisms.
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