Trial reportSkeletal radiology2025
Structural effects of whole body electromyostimulation on knee osteoarthritis: the EMSOAT Study.
Trial report in Skeletal radiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07352540 (Effects and Safety of Single Versus Triple Hyaluronic Acid Injections in the Treatment of Knee Osteoarthritis), which is not on this map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effects and Safety of Single Versus Triple Hyaluronic Acid Injections in the Treatment of Knee Osteoarthritis
Who cites it
1 citing paper in PubMed.
- The 18th international workshop on osteoarthritis imaging. Structure and pain: Where are we today?Osteoarthritis imaging · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
Abstract
objectiveWhole-body electromyostimulation (WB-EMS) might be an alternative option to conventional strength training for patients with knee osteoarthritis (OA). Our aim was to compare structural changes of knee OA between patients treated with WB-EMS and a control group (CG) treated with a standard of care approach. MATERIAL AND
methodsSeventy-two overweight participants with symptomatic knee OA were assigned to either WB-EMS or CG. MRIs were acquired at baseline and 7 months using a 3 T system. MRIs were read according to the MRI Osteoarthritis Knee Score (MOAKS) instrument. Between-group differences in regard to change in cartilage, bone marrow lesions (BMLs), osteophytes, meniscus damage and extrusion, and markers of inflammation were analyzed using Fisher's Exact and Wilcoxon Rank Sum tests.
resultsFewer knees in the WB-EMS groups showed cartilage worsening compared to the CG (18% vs. 40%, p = 0.046). There were fewer knees in the WB-EMS group showing an increase in BML size score of ≥ 1 (30% vs 46%, p = 0.43). Regarding prevalent BMLs that showed improvement, no change, or worsening, no differences were seen (p = 0.56). Little osteophyte and meniscal changes were observed during the observational period. Differences regarding change in inflammatory markers were not significant.
conclusionWhile there was a difference with fewer subregions showing worsening cartilage damage in the WB-EMS group, no significant differences were observed for change in BMLs, inflammation, osteophytes, and meniscal parameters. The observed improvement in clinical outcome parameters in favor of the WB-EMS group is likely due to other effects than improvement or less worsening of structural changes.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.