ReviewRadiologie (Heidelberg, Germany)2025
[SAPHO-Synovitis, acne, pustulosis, hyperosteosis, osteitis].
Review in Radiologie (Heidelberg, Germany), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- SAPHO syndrome and pustular skin diseases: shared inflammatory circuits, divergent tissue outcomes, and the limits of a spectrum model.Frontiers in immunology · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
clinical/methodological problemSAPHO (synovitis, acne, pustulosis, hyperosteosis, osteitis) is a rare rheumatological disease characterized by combined osteoarticular and dermatological manifestations. Due to the nonspecific clinical presentation and skin findings, which may occur nonsimultaneously to the osteoarticular manifestations, diagnosis is usually delayed. Imaging plays a crucial role in identifying characteristic changes and distinguishing from differential diagnoses. STANDARD RADIOLOGICAL PROCEDURES: X‑ray diagnostics, computed tomography (CT), and skeletal scintigraphy are established procedures for detecting typical osseous changes such as hyperostosis, sclerosis, and osteitis. Magnetic resonance imaging (MRI) allows early detection of inflammatory bone and soft tissue changes. METHODOLOGICAL INNOVATIONS/PERFORMANCE: Whole-body MRI is used for the systematic detection of multifocal lesions. Compared to scintigraphy, MRI offers the possibility of differentiating between active and inactive lesions without the use of ionizing radiation. ACHIEVEMENTS: Whole-body MRI is an important addition to conventional methods, especially for the early and noninvasive assessment of active disease processes and is an integral part of diagnostic evaluation. RECOMMENDATION FOR PRACTICE: In cases where the differential diagnosis is unclear, histological evaluation of the bone lesions must be performed.
Indexed as
Identifiers
40694075What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.