Planktonic anammox bacteria toward a better understanding of ecophysiological traits and harnessing the untapped potential as a bioresource.

Yantong Liu, Mingda Zhou, Jiawei Liu, Han Wang, Zibin Li, Yayi Wang

Abstract readReview

In one paragraph

Review in Bioprocess and biosystems engineering, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yantong LiuState Key Laboratory of Pollution Control and Resources Reuse, Shanghai Institute of Pollution Control and Ecological Security, Tongji University, Shanghai, 200092, China.

Mingda ZhouState Key Laboratory of Pollution Control and Resources Reuse, Shanghai Institute of Pollution Control and Ecological Security, Tongji University, Shanghai, 200092, China.

Jiawei LiuState Key Laboratory of Pollution Control and Resources Reuse, Shanghai Institute of Pollution Control and Ecological Security, Tongji University, Shanghai, 200092, China.

Han WangState Key Laboratory of Pollution Control and Resources Reuse, Shanghai Institute of Pollution Control and Ecological Security, Tongji University, Shanghai, 200092, China. hanw@tongji.edu.cn.

Zibin LiState Key Laboratory of Pollution Control and Resources Reuse, Shanghai Institute of Pollution Control and Ecological Security, Tongji University, Shanghai, 200092, China.

Yayi WangState Key Laboratory of Pollution Control and Resources Reuse, Shanghai Institute of Pollution Control and Ecological Security, Tongji University, Shanghai, 200092, China. yayi.wang@tongji.edu.cn.

Funding

National Key R&D Program of China No. 2021YFC3200601the National Science Fund for Distinguished Young Scholars 52225001

6 · The paper itself

Abstract

Anaerobic ammonium-oxidizing (anammox) bacteria play a crucial role in biogeochemical nitrogen cycling and have been applied to wastewater treatment as a revolutionary nitrogen removal technology. Despite the successful application of anammox technology in engineering, our understanding of anammox bacteria in terms of their physiological and biochemical characteristics remains the tip of the iceberg, and challenges mainly arise from their slow growth rates and the absence of pure cultures. The development of enrichment cultures, particularly through membrane bioreactors, is important in addressing these challenges. In this review, we highlight the key factors that are vital for optimizing planktonic cell growth and preventing cell aggregation, i.e., calcium and magnesium concentration, oxygen level, and solids retention time, and propose the involved regulation strategies which help improve our understanding of the ecology of anammox bacteria and their competitive advantages, particularly in nitrogen-limited environments. Then, insights into the unique cellular structures of anammox bacteria (including anammoxosome and their distinct lipid membranes) and the complex metabolic pathways involving unique nitrogen intermediates were discussed, partially based on anammox planktonic cells. Finally, recent advances pertaining to non-traditional growth conditions and novel applications, such as ladderane lipid biosynthesis, extracellular polymeric substance production, and electro-anammox processes are discussed, underscoring their potential in innovative bioresource utilization beyond wastewater treatment. This review provides an in-depth understanding of planktonic cultivation techniques, growth dynamics, and biochemical characteristics of anammox bacteria, and highlights promising avenues for future research and application of valuable anammox bacteria resources, propelling their application in both ecological and engineered systems.

Indexed as

Ammonium CompoundsBacteriaBioreactorsPlanktonOxidation-ReductionAmmonium CompoundsAnammoxCell structureEnergy conservationMetabolismPlanktonic cells

Identifiers

PMID40694061

DOI10.3390/md17050273

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.