Evidence map›Paper›PMID 40694000›Full record

ReviewFEMS yeast research2025

Glycerol bioconversion to biofuel and value-added products by yeasts.

Kostyantyn Dmytruk, Marta Semkiv, Andriy Sibirny

Abstract readReview
In one paragraph

Review in FEMS yeast research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Kostyantyn DmytrukDepartment of Molecular Genetics and Biotechnology, Institute of Cell Biology, NAS of Ukraine, Drahomanov Street, 14/16, Lviv 79005, Ukraine.ORCID 0000-0003-3661-8913
Marta SemkivLeibniz Institute of Plant Genetics and Crop Plant Research (IPK), Corrensstr. 3, OT Gatersleben, D-06466 Seeland, Germany.ORCID 0000-0002-2780-7096
Andriy SibirnyDepartment of Molecular Genetics and Biotechnology, Institute of Cell Biology, NAS of Ukraine, Drahomanov Street, 14/16, Lviv 79005, Ukraine.ORCID 0000-0001-8579-1566

Funding

National Research Foundation of Ukraine 2021/41/B/NZ1/01224National Research Foundation of Ukraine 2023.04/0032Simons Foundation 1290613
6 · The paper itself

Abstract

Glycerol, a by-product of biodiesel production, is a versatile polyol used in various industries. Yeasts play a crucial role in converting glycerol into biofuels and value-added products, offering sustainable alternatives to chemical synthesis. This review explores glycerol metabolism in yeasts, focusing on its bioconversion into ethanol, isopropanol, lipids, organic acids, and polyols. Saccharomyces cerevisiae and Yarrowia lipolytica are prominent species for these processes, with metabolic engineering enhancing their efficiency. Ethanol production from crude glycerol, a by-product of the biodiesel industry, is cost-effective compared to traditional feedstocks, while lipid production by oleaginous yeasts supports biodiesel synthesis. Organic acids like succinic, citric, and lactic acids, along with polyols such as erythritol and mannitol, are produced through optimized pathways, achieving high yields. Crude glycerol, despite impurities, is a viable low-cost substrate, with yeast strains adapted to tolerate its contaminants. Challenges include improving strain tolerance and scaling up processes. Future research aims to refine metabolic engineering and fermentation strategies to maximize glycerol's potential as a renewable feedstock for industrial biotechnology.

Indexed as

BiofuelsGlycerolSaccharomyces cerevisiaeYarrowiaYeastsBiotransformationEthanolFermentationMetabolic EngineeringBiofuelsEthanolGlycerolbioconversionbiofuelglycerolorganic acidspolyolsyeast

Identifiers

PMID40694000
PMCPMC12315107

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.