Evidence map›Paper›PMID 40693794›Full record

ArticleMicrobiology spectrum2025

Multiple cross displacement amplification (MCDA) for rapid detection of toxigenic

Hui Hu, Xiaomei Zhang, Mengting Cai, Xiaojun Song, Hongrui Cheng, Fangya Zhai, Yulei Tai, Zheng Xu, Shan Lin, Yu Chen and 2 more

Abstract read
In one paragraph

Article in Microbiology spectrum, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Accelerated detection ofMicrobiology spectrum · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Hui Hu *School of Laboratory Medicine, Zhejiang Provincial People's Hospital (Affiliated People's Hospital), Hangzhou Medical College, Hangzhou, Zhejiang, China.
Xiaomei Zhang *School of Biotechnology and Biomolecular Sciences, University of New South Wales, Sydney, Australia.
Mengting CaiSchool of Laboratory Medicine, Zhejiang Provincial People's Hospital (Affiliated People's Hospital), Hangzhou Medical College, Hangzhou, Zhejiang, China.
Xiaojun SongSchool of Laboratory Medicine, Zhejiang Provincial People's Hospital (Affiliated People's Hospital), Hangzhou Medical College, Hangzhou, Zhejiang, China.
Hongrui ChengSchool of Laboratory Medicine, Zhejiang Provincial People's Hospital (Affiliated People's Hospital), Hangzhou Medical College, Hangzhou, Zhejiang, China.
Fangya ZhaiSchool of Laboratory Medicine, Zhejiang Provincial People's Hospital (Affiliated People's Hospital), Hangzhou Medical College, Hangzhou, Zhejiang, China.
Yulei TaiSchool of Laboratory Medicine, Zhejiang Provincial People's Hospital (Affiliated People's Hospital), Hangzhou Medical College, Hangzhou, Zhejiang, China.
Zheng XuSchool of Laboratory Medicine, Zhejiang Provincial People's Hospital (Affiliated People's Hospital), Hangzhou Medical College, Hangzhou, Zhejiang, China.
Shan LinSchool of Laboratory Medicine, Zhejiang Provincial People's Hospital (Affiliated People's Hospital), Hangzhou Medical College, Hangzhou, Zhejiang, China.ORCID 0000-0003-3978-6568
Yu ChenSchool of Laboratory Medicine, Zhejiang Provincial People's Hospital (Affiliated People's Hospital), Hangzhou Medical College, Hangzhou, Zhejiang, China.ORCID 0000-0003-0315-9415
Yun LuoSchool of Biotechnology and Biomolecular Sciences, University of New South Wales, Sydney, Australia.ORCID 0000-0001-7713-4849
Dazhi JinSchool of Laboratory Medicine, Zhejiang Provincial People's Hospital (Affiliated People's Hospital), Hangzhou Medical College, Hangzhou, Zhejiang, China.ORCID 0000-0002-2613-7844

Funding

Medical Scientific Research Foundation of Zhejiang Province, China 2024XY055Program for Major Science and Technology Medicine and Healthcare in Zhejiang WKJ-ZJ-2309Scientific Research Fund of Zhejiang Provincial Education Department Y202352661
6 · The paper itself

Abstract

Toxigenic

Indexed as

Clostridioides difficileClostridium InfectionsNucleic Acid Amplification TechniquesPoint-of-Care TestingBacterial ProteinsBacterial ToxinsEnterotoxinsFecesHumansLimit of DetectionReal-Time Polymerase Chain ReactionSensitivity and SpecificityBacterial ProteinsBacterial ToxinsEnterotoxinstoxB protein, Clostridium difficileMCDApoint-of-care testingtcdB genetoxigenic Clostridioides difficile

Identifiers

PMID40693794
PMCPMC12403592

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.