Evidence map›Paper›PMID 40693762›Full record

ArticleMicrobiology spectrum2025

The impact of temperature and relative humidity on SARS-CoV-2 airborne transmission in Syrian hamsters.

Chunmao Zhang, Zhendong Guo

Abstract read
In one paragraph

Article in Microbiology spectrum, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Chunmao ZhangChangchun Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Changchun, China.ORCID 0000-0002-7788-3935
Zhendong GuoChangchun Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Changchun, China.

Funding

National Natural Science Foundation of China 32000134
6 · The paper itself

Abstract

Numerous studies have analyzed the effect of temperature and humidity on COVID-19 transmission, but the findings are inconsistent. This was due to differences in research methodologies, study regions and periods, selected variables, and confounding factors. Using Syrian hamsters, we conducted an evaluation of the airborne transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) under various temperature and relative humidity combination conditions in a tightly controlled environmental chamber. We found that the airborne transmission of SARS-CoV-2 was moderately slowed in high temperature and high relative humidity conditions. This can be partially attributed to reduced replication in hamsters and the shortened survival time of the virus in the air. In this study, we have demonstrated that the transmission of SARS-CoV-2 among hamsters is co-modulated to some extent by temperature and relative humidity, and the effect is less pronounced than anticipated that high temperatures would block or substantially reduce SARS-CoV-2 airborne transmission.IMPORTANCEIn this study, we found that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) airborne transmission is to some extent co-modulated by temperature and humidity. However, solely relying on seasonal fluctuations in temperature and humidity is insufficient to substantially mitigate COVID-19 transmission, underscoring the critical need for sustained public health measures. Based on our findings in this hamster model, we infer that COVID-19 may have some seasonal patterns, but these patterns would not be as conspicuous as those of influenza. This insight has significant implications for the ongoing efforts in monitoring, preventing, and controlling the spread of COVID-19.

Indexed as

COVID-19HumidityTemperatureAnimalsCricetinaeDisease Models, AnimalHumansMesocricetusPandemicsSARS-CoV-2Virus Replicationairborne transmissionhumiditySARS-CoV-2seasonalitySyrian hamstertemperature

Identifiers

PMID40693762
PMCPMC12403763

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.