ArticleOrganic letters2025
Stereospecific Synthesis of Cyclobutanones and Spirohexanones via Formal [3 + 1] Cycloaddition of Cyclopropanones with Sulfur Ylides.
Article in Organic letters, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- Formal [1,5] Rearrangement of Cyclopropanone Hemiaminals: Synthesis of Tetrahydrobenzazepinone Derivatives.Organic letters · 2026Article
- Ring-Enlargement of in Situ Generated Cyclopropanones with Carbonyls and Imines: Synthesis of γ-Butyrolactones and -lactams.Organic letters · 2026Article
- Ring Enlargements of in Situ-Formed Cyclopropanones by Sulfoxonium Ylides: One-Pot Synthesis of Alkylidene Cyclobutanones.The Journal of organic chemistry · 2026Article
- Novel Sulfonium Reagents for the Modular Synthesis of Spiro[2.3]Hexanes and Heteroatom-Containing Analogues: Synthesis, Application, and Evaluation as Bioisosteres.Angewandte Chemie (International ed. in English) · 2026Article
- Stereospecific Synthesis of Cyclobutanones and Spirohexanones via Formal [3 + 1] Cycloaddition of Cyclopropanones with Sulfur Ylides.Organic letters · 2025Article
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
A concise synthetic route to enantioenriched cyclobutanones is reported via ring expansion of cyclopropanone surrogates with unstabilized sulfoxonium ylides. The reaction is shown to proceed with complete regio- and stereospecificity with chiral substrates, leading to optically active 2,3-disubstituted cyclobutanones where reversible enamine formation allowed for controlled equilibration to the thermodynamic
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Registered trials
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