Evidence map›Paper›PMID 40693566›Full record

SynthesisOtolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery2025

Comparing the Audiological Success of Bone Cement to Standard Ossiculoplasty Techniques: A Systematic Review and Meta-analysis.

Natasha Dowell, Shayma Begum, Christopher Coulson, Hannah Nieto, Jameel Muzaffar

Abstract readSystematic ReviewMeta-AnalysisComparative Study
In one paragraph

Synthesis in Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Natasha DowellCollege of Medical and Dental Sciences, University of Birmingham, Birmingham, UK.ORCID https://orcid.org/0009-0002-3289-1656
Shayma BegumCollege of Medical and Dental Sciences, University of Birmingham, Birmingham, UK.ORCID https://orcid.org/0009-0007-6060-3726
Christopher CoulsonDepartment of Ear, Nose and Throat Surgery, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK.ORCID https://orcid.org/0000-0002-3991-5473
Hannah NietoInstitute of Metabolism and Systems Research, University of Birmingham, Birmingham, UK.ORCID https://orcid.org/0000-0003-3088-7848
Jameel MuzaffarDepartment of Ear, Nose and Throat Surgery, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK.ORCID https://orcid.org/0000-0003-3065-0269

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo compare the audiological success and longevity of bone cement to standard ossiculoplasty techniques. DATA SOURCES: PubMed, Embase, Cochrane Library, Medline, and the Web of Science were systematically searched for studies from the date of inception to November 8, 2024. REVIEW

methodsTwo independent reviewers screened for eligibility. Inclusion criteria were full-text, English language publications. Human studies of any methodology except case series with fewer than five patients were included. The Preferred Reporting Items for Systematic Reviews and Meta-analyses reporting guidelines were followed. Data were pooled using a random-effects model using relative risk with 95% CIs. Prespecified primary outcomes compared the success of bone cement reconstruction at short and longer-term follow-up.

resultsA total of 27 studies met the eligibility criteria. Bone cement resulted in better audiological outcomes (postoperative mean air-bone gap < 20 dB HL) compared to incus interposition, risk ratio (RR): 1.26 (95% CI: 1.10-1.43). There was no difference in success between bone cement and partial ossicular replacement prosthesis (PORP), RR: 1.15 (95% CI: 0.94-1.41). The findings of this review suggest that bone cement remains successful at a longer-term follow-up.

conclusionBone cement outperforms incus interposition and is comparable to PORP for audiological outcomes. Audiological improvement is sustained into longer-term follow-up.

Indexed as

Bone CementsOssicular ReplacementHumansTreatment OutcomeBone Cementsbone cementglass ionomer cementhydroxyapatiteossiculoplasty

Identifiers

PMID40693566
PMCPMC12574626

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.