Evidence map›Paper›PMID 40693350›Full record

ArticleBioethics2025

Ethics of Identifying Individuals Involved in HIV Transmission Events by Phylogenetics in Molecular Surveillance.

Francisca Faber, Lucie Abeler-Dörner, Stephanie Johnson, Tess Johnson, Euzebiusz Jamrozik

Abstract read
In one paragraph

Article in Bioethics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Francisca FaberDivision of Neuropathology and Neurochemistry, Department of Neurology, Medical University of Vienna, Vienna, Austria.ORCID 0009-0008-5009-2835
Lucie Abeler-DörnerEthox Centre and Pandemic Sciences Institute, University of Oxford, Oxford, UK.
Stephanie JohnsonEthox Centre and Pandemic Sciences Institute, University of Oxford, Oxford, UK.
Tess JohnsonEthox Centre and Pandemic Sciences Institute, University of Oxford, Oxford, UK.ORCID 0000-0003-2071-4302
Euzebiusz JamrozikEthox Centre and Pandemic Sciences Institute, University of Oxford, Oxford, UK.ORCID 0000-0001-5940-602X

Funding

This study was funded in whole, or in part, by the Wellcome Trust [203132] and [221719]. The Trust and Confidence research programme at the Pandemic Sciences Institute at the University of Oxford is supported by an award from the Moh Foundation. For the purpose of Open Access, the author has applied a CC BY public copyright licence to any Author Accepted Manuscript version arising from this submission.Wellcome Trust
6 · The paper itself

Abstract

Molecular HIV surveillance, involving the collection and analysis of HIV genome sequences, has become an integral part of public health programmes in high-income countries. By employing phylogenetic analysis, molecular HIV surveillance can identify individuals and their positions within networks of HIV transmission. While the primary aim of molecular surveillance is to yield public health benefits, such as linking people to care and reducing transmission, it also poses risks and potential infringements on individual privacy and liberty. This paper examines the ethical implications of using phylogenetics to identify individuals involved in multiple transmission events in high-income countries. Although public health responses tailored to such individuals can significantly reduce further transmission, these individuals often face multiple intersecting vulnerabilities and bear the greatest risks associated with molecular surveillance. We analyze the risks related to privacy, stigma, mistrust, criminalization, and liberty infringements, alongside the benefits of preventing further transmission and increasing healthcare engagement for people living with HIV. We conclude by outlining plausible and ethically acceptable policy options for molecular surveillance practice.

Indexed as

HIVHIV InfectionsPhylogenyConfidentialityHumansPrivacyPublic HealthSocial StigmaethicsHIVmolecular surveillancephylogeneticsrisk–benefit analysis

Identifiers

PMID40693350
PMCPMC12411990

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.