ArticleJournal of experimental orthopaedics2025
The role of arthroscopy in intra-articular adipose tissue-derived mesenchymal stem cells for the treatment of early-stage knee osteoarthritis: A bicentric retrospective comparative study.
Article in Journal of experimental orthopaedics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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Who cites it
1 citing paper in PubMed.
- The role of arthroscopy in intra-articular adipose tissue-derived mesenchymal stem cells for the treatment of early-stage knee osteoarthritis: A bicentric retrospective comparative study.Journal of experimental orthopaedics · 2025Article
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7 authors.
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Abstract
Purpose: To determine the difference in clinical scores and re-intervention rates in patients receiving intra-articular adipose-derived mesenchymal stromal cells (AD-MSCs) as a stand-alone treatment for knee osteoarthritis (OA) compared to patients receiving the same treatment following arthroscopic debridement and lavage. Methods: Internal records at two orthopaedic centres were reviewed, and all consecutive patients with Kellgren-Lawrence II-III knee OA who had received intra-articular AD-MSC during 2017-2018 were included. The patients were stratified into two cohorts depending on whether they also received debridement arthroscopy. Patients were evaluated with the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) and visual analogue scale (VAS) scores as well as re-intervention rates with a last available follow-up of 5 years after the intra-articular AD-MSC injection. Results: A total of 135 patients were enroled, 66 (49%) patients were male and 69 (51%) were female. The mean age at the time of intervention was 66 (range: 43-81) years. About half of the cohort ( Conclusion: Overall, debridement arthroscopy with AD-MSC is favoured over stand-alone MSC in Kellgren-Lawrence I-III knee OA. Level of Evidence: Level III, retrospective comparative study.
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