Evidence map›Paper›PMID 40693208›Full record

ArticleSAGE open medical case reports2025

Massive retropharyngeal goiter: Case presentation and literature review of a rare entity.

Russel T Wagner, Sammy Khalili, Neil S Mundi

Abstract readCase Reports
In one paragraph

Article in SAGE open medical case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Russel T WagnerIntent Medical Group, Department of Neurosciences, Endeavor Health, Northwest Community Hospital, Arlington Heights, IL, USA.
Sammy KhaliliIntent Medical Group, Department of Neurosciences, Endeavor Health, Northwest Community Hospital, Arlington Heights, IL, USA.
Neil S MundiIntent Medical Group, Department of Neurosciences, Endeavor Health, Northwest Community Hospital, Arlington Heights, IL, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Retropharyngeal goiters are uncommon entities characterized by the presence of thyroid tissue in the retropharyngeal space. We present the case of an 89-year-old female with a history of dysphagia and hoarseness of voice. Imaging revealed a massive goiter extending into the retropharyngeal and retrosternal spaces. The patient underwent a total thyroidectomy with transcervical removal of the substernal component. Our analysis of 13 documented cases (14 including ours) of retropharyngeal multinodular goiters reveals a range of presentations with dysphagia, dysphonia, and dyspnea being the most common symptoms. Total thyroidectomy emerged as the prevailing management approach, though there are surgical challenges including airway management and potential pharyngeal musculature injury. The most plausible mechanism for retropharyngeal goiter development is progressive displacement due to glandular enlargement. This case highlights the clinical considerations and perioperative strategies required for the management of retropharyngeal goiters, particularly in elderly patients with significant anatomic distortion. Additionally, we provide a comparative literature review to further characterize the presentation and surgical management of this rare entity.

Indexed as

dysphagiadysphoniaembryological anomaliesgoiter displacementmultinodular goiterrespiratory distressretropharyngeal goitersurgical complicationstotal thyroidectomytracheal compression

Identifiers

PMID40693208
PMCPMC12277667

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.