Evidence map›Paper›PMID 40692976›Full record

ArticleDrugs in context2025

Simulated client study on the dispensing practices for narcotic and psychotropic medications in community drug outlets in Ethiopia.

Tirsit Ketsela Zeleke, Minichil Chanie Worku, Bantayehu Addis Tegegne, Fasil Bayafers Tamene, Gebremariam Wulie Geremew, Samuel Agegnew Wondm, Aschalew Mulatu Tefera, Ayelign Eshete Fitgu, Tekletsadik Tekleslassie Alemayehu, Muluken Adela Alemu and 3 more

Abstract read
In one paragraph

Article in Drugs in context, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

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No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

13 authors.

Tirsit Ketsela ZelekeDepartment of Pharmacy, College of Health Sciences, Debre Markos University, Debre Markos, Ethiopia.ORCID https://orcid.org/0000-0003-3528-0703
Minichil Chanie WorkuDepartment of Pharmaceutical Chemistry, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia.
Bantayehu Addis TegegneDepartment of Pharmacy, College of Health Sciences, Debre Markos University, Debre Markos, Ethiopia.
Fasil Bayafers TameneDepartment of Pharmacy, College of Health Sciences, Debre Markos University, Debre Markos, Ethiopia.
Gebremariam Wulie GeremewDepartment of Clinical Pharmacy, School of Pharmacy, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia.
Samuel Agegnew WondmDepartment of Pharmacy, College of Health Sciences, Debre Markos University, Debre Markos, Ethiopia.
Aschalew Mulatu TeferaDepartment of Pharmacognosy, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia.
Ayelign Eshete FitguDepartment of Social and Administrative Pharmacy, School of Pharmacy, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia.
Tekletsadik Tekleslassie AlemayehuDepartment of Social and Administrative Pharmacy, School of Pharmacy, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia.
Muluken Adela AlemuPharmacy Education and Clinical Service Directorate, College of Health Sciences, Debre Tabor University, Debre Tabor, Ethiopia.
Rahel Belete AbebeDepartment of Clinical Pharmacy, School of Pharmacy, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia.
Kale GubaeDepartment of Pharmacy, College of Health Sciences, Debre Markos University, Debre Markos, Ethiopia.
Abraham TeymDepartment of Environmental Health, College of Health Sciences, Debre Markos University, Debre Markos, Ethiopia.ORCID https://orcid.org/0000-0001-5954-0923

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Dispensing prescription-only medications without a valid prescription poses significant public health risks, including inappropriate drug use, adverse drug reactions and medication dependence. Narcotics and psychotropic drugs are particularly vulnerable to misuse. Despite this, limited data exist on the dispensing practices of these medications at community drug retail outlets in Ethiopia. This study aimed to assess the extent and factors of non-prescription dispensing of narcotic and psychotropic medications at community drug retail outlets in Ethiopia. Methods: An observational cross-sectional study was conducted using the simulated client method from June 1, 2023, to September 30, 2023, in Debre Markos town, Ethiopia. Three trained volunteer pharmacy professionals acted as simulated clients. A validated simulated client approach was used to request medications through three different scenarios: symptom-based (depression), direct request by name and request by presenting a medication package. Results: A total of 109 requests were made by the simulated clients at 38 community drug retail outlets during three rounds of observations. The rates of non-prescription dispensing were 28.9% for depression simulation, 60.5% for direct name requests and 81.6% for package-based requests. A total of nine types of narcotic and psychotropic medications were dispensed without prescription, the most common of which were amitriptyline, followed by tramadol, carbamazepine, pethidine and haloperidol. Conclusion: This study revealed a high prevalence of non-prescription dispensing of narcotic and psychotropic medications, particularly in response to assertive client requests. Urgent regulatory measures are needed to ensure adherence to prescription-only policies, especially for frequently dispensed drugs such as amitriptyline, tramadol and chlorpromazine.

Indexed as

community pharmaciesnarcotic drugsnon-prescription dispensingpsychotropic medicationssimulated client method

Identifiers

PMID40692976
PMCPMC12279291

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.