Evidence map›Paper›PMID 40692942›Full record

ArticleApplied mathematical modelling2026

State-space formulations to understand the nonlinear viscoelastic mechanical behavior of tricuspid valve chordae tendineae.

Li-Wei Liu, Yuan-Jyun Shih, Chih-Ming Chao, Michael J Burkhart, Colton J Ross, Chung-Hao Lee

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Article in Applied mathematical modelling, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

6 authors.

Li-Wei LiuDepartment of Civil Engineering, National Taiwan University, Taipei 10617, Taiwan.
Yuan-Jyun ShihDepartment of Engineering Science, National Cheng Kung University, Tainan 70101, Taiwan.
Chih-Ming ChaoDepartment of Engineering Science, National Cheng Kung University, Tainan 70101, Taiwan.
Michael J BurkhartSchool of Aerospace and Mechanical Engineering, The University of Oklahoma, Norman, OK 73019, USA.
Colton J RossSchool of Aerospace and Mechanical Engineering, The University of Oklahoma, Norman, OK 73019, USA.
Chung-Hao LeeDepartment of Bioengineering, University of California, Riverside, Riverside CA 92521.

Funding

Improving outcomes in endovascular treatment of intracranial aneurysms: Combining additive manufacturing, in-silico modeling, and shape memory polymersR01HL159475 · NHLBI · UNIVERSITY OF OKLAHOMA · PI Chung-Hao Lee · 2022 to 2026
$3.3M
Integrate Data-Driven Modeling and Multi-scale Measures Towards Tissue FunctionR01GM157589 · NIGMS · LEHIGH UNIVERSITY · PI YUE YU · 2024 to 2026
$890k
American Heart Association-American Stroke Association 16SDG27760143American Heart Association-American Stroke Association 24IVPHA1283213 - CHUNG-HAO LEENHLBI NIH HHS R01 HL159475NIGMS NIH HHS R01 GM157589
6 · The paper itself

Abstract

The state-space representation is an alternative description of a dynamical system to the input-output representation in the systems theory. In this paper, we used the state-space representation to study the mechanical behavior of the tricuspid valve (TV) chordae tendineae. The TV chordae behave viscoelastic features under the loading; hence, we cast the generalized Kelvin model with an additional nonlinear spring into the state-space description to develop the solution under different loading conditions. With the aid of the state-space representation, the closed-form solution of the displacement response can be analytically obtained, for the case of force control. Taking into account the in-resistance of compression of biological soft tissue, the exact response to a sinusoidal cyclic force with non-zero mean was

Indexed as

Chordae tendineaedynamic mechanical testthe nonlinear generalized Kelvin modelthe state-space representationviscoelastic model

Identifiers

PMID40692942
PMCPMC12276938

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