ArticleFrontiers in oncology2025
Great saphenous vein leiomyosarcoma: a rare case report and literature review.
Article in Frontiers in oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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3 citing papers in PubMed.
- Multiple leiomyosarcoma of great saphenous vein with lung metastasis.Journal of cardiothoracic surgery · 2026Article
- Management of Great Saphenous Vein and Inferior Vena Cava Leiomyosarcomas: Two Surgical Case Reports and Literature Review.Journal of clinical medicine · 2026Article
- Leiomyosarcomas of the Great Saphenous Vein: Diagnostic and Therapeutic Strategies to Prevent Unplanned Excisions and Improve Oncologic, Functional, and Psychological Outcomes.Diseases (Basel, Switzerland) · 2025Article
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6 authors.
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Abstract
Great saphenous vein leiomyosarcoma is an extremely rare tumor clinically, which is often misdiagnosed as superficial venous thrombosis due to atypical clinical manifestations. This report describes a rare presentation of great saphenous vein leiomyosarcoma in a 37-year-old man who was referred to our hospital due to a gradually enlarging painless mass on his left shank. Ultrasound revealed that the mass in the left calf was a solid tumor originating from the left great saphenous vein. He underwent radical resection for the mass ultimately. Subsequent histopathological and immunohistochemical analyses resulted in a conclusive diagnosis of primary leiomyosarcoma originating from the great saphenous vein. There are only 56 cases of great saphenous vein leiomyosarcoma reported in medical databases worldwide at present, which are summarized and analyzed here.
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