ArticleFrontiers in pediatrics2025
The impact of a multi-micronutrient nutritional formula combined with cognitive behavioral therapy in managing symptoms of children with attention deficit hyperactivity disorder.
Article in Frontiers in pediatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Attention-Deficit/Hyperactivity Disorder (ADHD) characterized by symptoms of inattention, hyperactivity, and impulsivity, with substantial impacts on a child's academic performance, social interactions, and overall quality of life. This study investigates the impact of combining a multi-micronutrient nutritional formula (MNF) with cognitive behavioral therapy (CBT) in managing ADHD symptoms in children. Methods: In a retrospective analysis of 220 children aged 6-14 years diagnosed with ADHD, patients were divided into two groups: the MNF group ( Results: Both groups were comparable at baseline in terms of demographics and ADHD symptom severity. Post-treatment analyses revealed greater reductions in attention deficit scores, hyperactivity/impulsivity scores, and oppositional symptoms scores in the MNF-CBT group compared to the MNF group. Conduct scores were lower in the MNF-CBT group than in the MNF group, and learning scores also showed a similar pattern of reduction. Functional impairments across various daily activities, as measured by the D-DTODS, were also reduced in the MNF-CBT group. No adverse events or safety concerns were observed during the intervention period. Conclusion: The combination of multi-micronutrient supplementation with CBT shows potential in alleviating both neurochemical deficiencies and behavioral dysregulation in children with ADHD. These findings suggest that this integrated approach may be beneficial for managing ADHD symptoms.
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