Evidence map›Paper›PMID 40692779›Full record

ArticleFrontiers in immunology2025

Cannabinoids and alcohol co-exposure modulate pathogen-induced pulmonary immune responses.

De'Jana Parker, Vijay Sivaraman

Abstract read
In one paragraph

Article in Frontiers in immunology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

De'Jana ParkerDepartment of Molecular, Cellular and Developmental Biology, University of Michigan, Ann Arbor, MI, United States.
Vijay SivaramanDepartment of Biological & Biomedical Sciences, North Carolina Central University, Durham, NC, United States.

Funding

Understanding Perceptions of HIV Risk, PrEP, and PrEP use among African American Women Attending an HBCUU54MD012392 · NIMHD · NORTH CAROLINA CENTRAL UNIVERSITY · PI Cherise Baldwin Harrington · 2017 to 2026
$38.1M
Translational Research Support CoreP30ES025128 · NIEHS · NORTH CAROLINA STATE UNIVERSITY RALEIGH · PI Sue Fenton · 2015 to 2026
$18.3M
RC3 Ethanol-Cannabinoid Interaction in the Regulation of NeurogenesisU54AA019765 · NIAAA · NORTH CAROLINA CENTRAL UNIVERSITY · PI COLE, GREGORY JAY · 2010 to 2019
$8.7M
NIAAA NIH HHS U54 AA019765NIEHS NIH HHS P30 ES025128NIMHD NIH HHS U54 MD012392
6 · The paper itself

Abstract

Both alcohol and cannabinoid misuse cause substantial societal problems individually, and cannabis is the most popular illicit drug used simultaneously with alcohol. The role of endocannabinoids (eCB) and cognate receptors in the regulation of inflammation is clinically relevant; however, the role of cannabinoid receptors (CBRs) specifically in pulmonary inflammation and associated lung pathobiology remains elusive. For this study, we investigated the effects of binge cannabinoid exposure on pathogen-induced pulmonary inflammation. We also describe a binge ethanol + cannabinoid adolescent mouse model of pathogen-induced pulmonary inflammation by

Indexed as

CannabinoidsEthanolKlebsiella InfectionsKlebsiella pneumoniaeLungPneumoniaPneumonia, BacterialAnimalsDisease Models, AnimalMaleMiceMice, Inbred C57BLReceptors, CannabinoidCannabinoidsEthanolReceptors, Cannabinoidalcoholcannabinoidsimmune responsespolysubstance misusepulmonary inflammation

Identifiers

PMID40692779
PMCPMC12277145

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.