Evidence map›Paper›PMID 40692775›Full record

ArticleFrontiers in immunology2025

Germline encoded residues dominate the interaction of a human monoclonal antibody with decorin binding protein A of

Michael J Rudolph, Beatrice M Muriuki, Yang Chen, David J Vance, Clint Vorauer, Carol Lyn Piazza, Grace Freeman-Gallant, Rachel M Golonka, Gianna Mirabile, Miklos Guttman and 2 more

Abstract read
In one paragraph

Article in Frontiers in immunology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Michael J Rudolph *New York Structural Biology Center, New York, NY, United States.
Beatrice M Muriuki *Department of Medicine, University of Massachusetts Chan Medical School, Worcester, MA, United States.
Yang ChenNew York Structural Biology Center, New York, NY, United States.
David J VanceDivision of Infectious Diseases, Wadsworth Center, NY State Department of Health, Albany, NY, United States.
Clint VorauerDepartment of Medicinal Chemistry, University of Washington, Seattle, WA, United States.
Carol Lyn PiazzaDivision of Infectious Diseases, Wadsworth Center, NY State Department of Health, Albany, NY, United States.
Grace Freeman-GallantDivision of Infectious Diseases, Wadsworth Center, NY State Department of Health, Albany, NY, United States.
Rachel M GolonkaDepartment of Medicine, University of Massachusetts Chan Medical School, Worcester, MA, United States.
Gianna MirabileDepartment of Biomedical Sciences, University at Albany, Albany, NY, United States.
Miklos GuttmanDepartment of Medicinal Chemistry, University of Washington, Seattle, WA, United States.
Lisa A CavaciniDepartment of Medicine, University of Massachusetts Chan Medical School, Worcester, MA, United States.
Nicholas J MantisDivision of Infectious Diseases, Wadsworth Center, NY State Department of Health, Albany, NY, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

During the course of Lyme disease, humans mount a robust and sustained antibody response against dozens of

Indexed as

Adhesins, BacterialAntibodies, BacterialAntibodies, MonoclonalBorrelia burgdorferiLyme DiseaseAnimalsCrystallography, X-RayEpitope MappingHumansMiceProtein BindingAdhesins, BacterialAntibodies, BacterialAntibodies, MonoclonalDdpB protein, Borrelia burgdorferiBorrelia (Borreliella) burgdorferihumanlyme antibodiesmousevaccines

Identifiers

PMID40692775
PMCPMC12277278

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.