Evidence map›Paper›PMID 40692676›Full record

ArticleGut microbiome (Cambridge, England)2025

The effects of inorganic nitrate and inulin co-ingestion on circulating metabolites and blood pressure in young adults: a pilot double-blind randomised crossover trial.

Jessica Virgili, Gwenaelle Le Gall, Anni Vanhatalo, Bert Bond, David Vauzour, Luciana Torquati

Erratum issuedAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Gut microbiome (Cambridge, England), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Jessica VirgiliUniversity of Exeter Medical School, Faculty of Health and Life Sciences, Department of Public Health and Sport Sciences, University of Exeter, St Lukes Campus, Heavitree Road, Exeter EX1 2LU, UK.ORCID https://orcid.org/0000-0003-2899-0766
Gwenaelle Le GallNorwich Medical School, Faculty of Medicine and Health Sciences, University of East Anglia, Norwich NR4 7TJ, UK.
Anni VanhataloUniversity of Exeter Medical School, Faculty of Health and Life Sciences, Department of Public Health and Sport Sciences, University of Exeter, St Lukes Campus, Heavitree Road, Exeter EX1 2LU, UK.
Bert BondUniversity of Exeter Medical School, Faculty of Health and Life Sciences, Department of Public Health and Sport Sciences, University of Exeter, St Lukes Campus, Heavitree Road, Exeter EX1 2LU, UK.
David VauzourNorwich Medical School, Faculty of Medicine and Health Sciences, University of East Anglia, Norwich NR4 7TJ, UK.ORCID https://orcid.org/0000-0001-5952-8756
Luciana TorquatiUniversity of Exeter Medical School, Faculty of Health and Life Sciences, Department of Public Health and Sport Sciences, University of Exeter, St Lukes Campus, Heavitree Road, Exeter EX1 2LU, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dietary patterns enriched in fermentable fibre (such as inulin) and inorganic nitrate are linked to cardiovascular benefits, possibly mediated by gut microbiota-derived bioactive compounds including short-chain fatty acids (SCFAs) and nitric oxide (NO). However, the potential synergistic effects remain unclear. We conducted a randomised, double-blind, crossover study to investigate the acute effects of inulin (15 g; INU), nitrate (400 mg; NO

Indexed as

acetatefermentable fibregut microbiomenitratevascular health

Identifiers

PMID40692676
PMCPMC12277101

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.